教授　武藤　倫弘

 

准教授	宮本　真吾
講師	渡邉　元樹
助教（学内講師）	飯泉　陽介
助教	増田　光治

 

がん予防剤の実用化に向けたがんハイリスクグループに対する臨床介入試験

 

遺伝子の発現制御機構に基づいた新しいがんの予防法あるいは前がん病変検査・治療法の開発

 

リスク因子や分子機構に基づき、副作用軽減・併用による相互作用・感受性亢進・耐性克服を意図したがん分子標的併用予防法の開発
 

産学連携によるドラッグリポジショニング、機能性食品による予防法の探索と開発

 

ケモプロテオミクス・ケモインフォマティクスによる天然物のがん予防効果の機序解明および新規がん予防成分のin silicoスクリーニングへの展開

 

がん特異的代謝異常に着目した新規がん予防法の開発

 

変異遺伝子による代謝調節に着目した発がん予防物質検索、in vivo有効性評価

 

ケミカルバイオロジーの手法を用いた、がん予防剤や機能性食品成分の標的タンパク質の同定と精密な作用機構解析

 

論文業績

 

2024年

1. Gotoda T, Ishikawa H, Kusano C, Suzuki S, Ohnishi H, Sugano K, Matsuyama Y. Randomized controlled trial comparing the costs of gastric cancer screening systems between serological risk-based upper gastrointestinal endoscopy and the existing barium photofluorography: gastric cancer screening labeled by serum examination in place of aged gastric cancer organized screening systems (GALAPAGOS study). Gastric Cancer. 27(1):36-48, 2024　Jan. (IF=5.1)

 

2. Hori K, Katada C, Okada H, Katagiri A, Matsuo Y, Yokoyama T, Yano T, Suzuki H, Shimizu Y, Furue Y, Nakanishi H, Koike T, Takizawa K, Hirao M, Yoshii T, Yamanouchi T, Kawakubo H, Kobayashi N, Shimoda T, Ochiai A, Ishikawa H, Yokoyama A, Muto M. Association between continuous cessation or reduction of drinking alcohol and improvement of multiple dysplastic lesions in patients with esophageal squamous cell carcinoma after endoscopic resection. Esophagus. 21(1):31-40, 2024Jan. (IF=3.8)

 

3. Miyakura Y, Yamaguchi T, Lefor AK, Tamaki S, Takao A, Takao M, Mori Y, Chikatani K, Ishida H, Kono M, Takeuchi Y, Ishikawa H, Nagasaki T, Sasaki K, Matsubara T, Hirata K, Taniguchi T, Tanakaya K, Tomita N, Ajioka Y. Clinical features and distribution of the APC variant in duodenal and ampullary polyps in patients with familial adenomatous polyposis: A Multicenter Retrospective Cohort Study in Japan. Int J Clin Oncol. 29(2):169-178, 2024　Feb. (IF=2.8)

 

4. Yao K, Yao T, Uedo N, Doyama H, Ishikawa H, Nimura S, Takahashi Y. E-learning System to Improve the Endoscopic Diagnosis of Early Gastric Cancer. Clin Endosc. 57(3):283-292, 2024　May. (IF=2.3)

 

５. Saito Y, Sakamoto T, Dekker E, Pioche M, Probst A, Ponchon T, Messmann H, Dinis-Ribeiro M, Matsuda T, Ikematsu H, Saito S, Wada Y, Sano Y, Fujishiro M, Murakami Y, Ishikawa H, Inoue H, Tanaka S, Tajiri H, and IEE-JNET Group. First report from the International Evaluation of Endoscopic classification Japan NBI Expert Team: International multicenter web trial. Dig Endosc. 36(5):591-599, 2024　May. (IF=4.7)

 

6. Sano Y, Hotta K, Matsuda T, Murakami Y, Fujii T, Kudo SE, Oda Y, Ishikawa H, Saito Y, Kobayashi N, Sekiguchi M, Ikematsu H, Katagiri A, Konishi K, Takeuchi Y, Iishi H, Igarashi M, Kobayashi K, Sada M, Osera S, Shinohara T, Yamaguchi Y, Hasuda K, Morishima T, Miyashiro I, Shimoda T, Taniguchi H, Fujimori T, Ajioka Y, Yoshida S; Japan Polyp Study (JPS) Workgroup. Endoscopic Removal of Premalignant Lesions Reduces Long-Term Colorectal Cancer Risk: Results from the Japan Polyp Study. Clin Gastroenterol Hepatol. 22(3):542-551.e3, 2024　Mar. (IF=12)

 

7. Hasuo H, Mori K, Matsuoka H, Sakuma H, Ishikawa H. An Estimation Formula for Resonance Frequency Using Sex and Height for Healthy Individuals and Patients with Incurable Cancers. Appl Psychophysiol Biofeedback. 49(1):125-132, 2024　Mar. (IF=2.4)

 

8. Kato M, Ono S, Kawada K, Dohi O, Kitamura S, Koike T, Hori S, Kanzaki H, Murao T, Yagi N, Sasaki F, Hashiguchi K, Oka S, Katada K, Shimoda R, Mizukami K, Suehiro M, Takeuchi T, Katsuki S, Tsuda M, Naito Y, Kawano T, Haruma K, Mori K, Ishikawa H. Diagnostic Performance of Linked Color Imaging for Gastric Cancer by Helicobacter pylori Infection Status: a Sub-analysis of the Large-Scale, Multicenter Randomized Controlled Trial LCI-FIND. Helicobacter. 29(2):e13080, 2024　Mar-Apr. (IF=4.3)

 

9. Yoshida N, Suzuki S, Inoue K, Aniwan S, Chiu HM, Laohavichitra K, Chirapongsathorn S, Yamamura T, Kuo CY, Ang TL, Takezawa T, Rerknimitr R, Ishikawa H; ATLAS Trial Group. Analysis of the characteristics of coexisting lesions in colorectal cancer patients in an international study: A subgroup analysis of the ATLAS trial. Digestion. 105(4):280-290, 2024　Apr. (IF=3.6)

 

10. Miyazaki H, Dohi O, Maeda E, Tomioka A, Yoshida N, Morinaga Y, Itoh Y, Ishikawa H. Multiple duodenal epithelial tumors in a patient with polymerase proofreading-associated polyposis in POLE variant. Clin J Gastroenterol. 17(3):425-428, 2024. Jun(IF=0.9)

 

11. Yoshida N, Maeda-Minami A, Ishikawa H, Mutoh M, Tomita Y, Kobayashi R, Hashimoto H, Inoue K, Hirose R, Dohi O, Itoh Y, Mano Y. Prevalence of colonoscopy in Japan using a large-scale health claims data compared to esophagogastroduodenoscopy. J Gastroenterol. 2024 Jun;59(6):457-467. (IF-5.5)

 

12. UrabeY, Ishikawa H, Ishikawa A, Ishiguro S, Ishibashi K, Arihiro K, Mutoh M, Oka S. Two cases of increased gastrointestinal polyps in familial adenomatous polyposis following antiacid agent intake. Case Rep Gastroenterol. 2024 May 31;18(1):293-298. (IF-0.6)

 

13. Takasu A, Suzuki S, Kusano C, Ishikawa H, Gotoda T, Kogure H. Daily diet and nutrition risk factors for gastric cancer incidence in the Japanese population. Gut Liver. 18(4):602-610, 2024　Jul. (IF=3.2)

 

14. Kusano C, Gotoda T, Ishikawa H, Suzuki S, Ikehara H, Matsuyama Y. Gastric Cancer Detection Rates using Gastrointestinal Endoscopy with Serological Risk Stratification: A Randomized Controlled Trial. Gastrointest Endosc. 100(1):55-63.e1, 2024. Jul(IF=7.5)

 

15. Hasegawa I, Suzuki S, Yamamura T, Aniwan S, Chiu HM, Laohavichitra K, Chirapongsathorn S, Kuo CY, Yoshida N, Ang TL, Takezawa T, Rerknimitr R, Ishikawa H, Gotoda T; ATLAS trial Group. Linked color imaging improves colorectal lesion detection especially for low-performance endoscopists: An international trial in Asia. J Gastroenterol Hepatol. 39(7):1374-1381, 2024. Jul(IF=3.4)

 

16. Hirata K, Yoshida K, Katada C, Watanabe A, Tsushima T, Yamaguchi T, Yamamoto S, Ishikawa H, Sato Y, Imamura CK, Tanigawara Y, Ito Y, Kato K, Kitagawa Y, Hamamoto Y. Definitive chemoradiotherapy with paclitaxel for locally advanced esophageal squamous cell carcinoma in older patients (PARADISE-1): A phase I trial. BMC Cancer. 24(1):873, 2024　Jul. (IF=3.4)

 

17. Tsuji S, Doyama H, Kobayashi N, Ohata K, Takeuchi Y, Chino A, Takamaru H, Tsuji Y, Hotta K, Harada K, Ikematsu H, Uraoka T, Murakami T, Katagiri A, Hori S, Michida T, Suzuki T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Saito Y. Outcomes of noncurative endoscopic submucosal dissection for T1 colorectal cancer: Prospective, multicenter, cohort study in Japan. Dig Endosc. 36(12):1369-1379, 2024　Aug. (IF=4.7)

 

18. Ono S, Yamamoto K, Ishibashi F, Fujimoto A, Urabe Y, Takeda T, Ishikawa H, Fujishiro M, Gotoda T, Kaminishi M, Sugano K. Red dichromatic imaging and linked color imaging as reliable image-enhanced endoscopic procedures for detecting the distal end of the palisade vessels in the columnar metaplastic mucosa of the gastroesophageal junction zone. J Gastroenterol. 59(8):647-657, 2024　Aug. (IF=5.5)

 

19. Ito S, Hotta K, Sekiguchi M, Takeuchi Y, Oka S, Yamamoto H, Shinmura K, Harada K, Uraoka T, Hisabe T, Sano Y, Kondo H, Horimatsu T, Kikuchi H, Kawamura T, Nagata S, Yamamoto K, Tajika M, Tsuji S, Kusaka T, Okuyama Y, Yoshida N, Moriyama T, Hasebe A, So S, Saito Y, Nakahira H, Ishikawa H, Matsuda T; C‐NET STUDY Group. Short-term outcomes of endoscopic resection for colorectal neuroendocrine tumors: Japanese multicenter prospective C-NET STUDY. Dig Endosc. 36(8):942-951, 2024　Aug. (IF=4.7)

 

20. Tanaka H, Uraoka T, Kobayashi N, Ohata K, Takeuchi Y, Chino A, Yamada M, Tsuji Y, Hotta K, Harada K, Ikematsu H, Murakami T, Tsuji S, Katagiri A, Hori S, Michida T, Suzuki T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Nagahara A, Saito Y. Short-term and long-term outcomes of submucosal dissection for residual or recurrent colorectal tumors after endoscopic resection: Analysis of a multicenter prospective study. Dig Endosc. 36(9):1003-1011, 2024　Sep. (IF=4.7)

 

21. Tan CK, Suzuki S, Ang TL, Koh XH, Wang LM, Aniwan S, Chiu HM,  Laohavichitra K, Chirapongsathorn S, Yamamura T, Kuo CY, Yoshida N, Takezawa T, Rerknimitr R, Ishikawa H, Gotoda T. Sessile serrated lesion prevalence and factors associated with their detection: a post-hoc analysis of a multinational randomized controlled trial from Asia. Endoscopy. 56(9):684-693, 2024　Sep. (IF=12.8)

 

22. Kawazoe M, Nanki T, Saeki K, Ishikawa H, Nakamura Y, Kawashima S, Ito S, Kodera M, Konda N, Kaname S, Harigai M. Nationwide epidemiological survey of polyarteritis nodosa in Japan in 2020. Mod Rheumatol. 34(6):1284-1287, 2024　Oct. (IF=1.9)

 

23. Kato C, Iizuka-Ohashi M, Honda M, Konishi E, Yokota I, Boku S, Mizuta N, Morita M, Sakaguchi K, Taguchi T, Watanabe M†, Naoi Y　Additional statin treatment enhances the efficacy of HER2 blockade and improves prognosis in Rac1-high/HER2-positive breast cancer　Biochim Biophys Acta Mol Basis Dis. 1870(8):167458, 2024. (†corresponding author)(IF=4.2)

 

24. Hamoya T, Kaminaga K, Igarashi R, Nishimura Y, Yanagihara H, Morioka T, Suzuki C, Abe H, Ohshima T, Imaoka T. Intravital microscopic thermometry of rat mammary epithelium by fluorescent nanodiamond. Nanoscale Horiz. 9(11):1938-1947, 2024. (IF= 6.6)

 

25. Shimamoto Y, Takeuchi Y, Ishiguro S, Nakatsuka S, Yunokizaki H, Ezoe Y, Shichijo S, Maekawa A, KanesakaT, Yamamoto S, Higashino K, Uedo N, Ishihara R, Mutoh M, Ishikawa H. Classification of fundic gland polyps for predicting gastric neoplasms in Helicobacter pylori-negative patients with familial adenomatous polyposis. Gastric cancer. 2024 Nov;27(6):1311-1319. (IF-5.1)

 

26. Katada C, Yokoyama T, Watanabe A, Hara H, Yoshii T, Fujii H, Yamaguchi H, Nakajima T, Izawa N, Ando T, Nomura M, Kojima T, Yamashita K, Kawakami S, Ishiyama H, Inoue Y, Sakamoto Y, Sasaki H, Ishikawa H, Hosokawa A, Hamamoto Y, Muto M, Tahara M, Koizumi W. Optimizing Organ-Preservation Strategies Through Chemotherapy-Based Selection in Esophageal Squamous Cell Carcinoma: Results From the CROC Multi-Institutional Phase 2 Clinical Trial. Int J Radiat Oncol Biol Phys. 120(5):1353-1362, 2024　Dec. (IF=6.5)

 

27. Takao A, Yamaguchi T, Eguchi H, Okazaki Y, Ishikawa H, Akagi K, Ishida H. Genetic testing of Japanese patients with serrated polyposis syndrome: a multicentric study. J Anus Rectum Colon. 8(4):348-355, 2024　Oct. (IF=1.5)

 

28. Hirata S, Hamada K, Iwamuro M, Mouri H, Miyahara K, Tsuzuki T, Yamauchi K, Kobayashi S, Takahashi S, Takenaka R, Hori S, Inoue M, Toyokawa T, Nishimura M, Ishiyama S, Miyaike J, Kato R, Matsubara M, Yunoki N, Kanzaki H, Kawahara Y, Okada H, Ishikawa H, Otsuka M; Okayama Gut Study Group. Rates and risk factors of bleeding after gastric endoscopic submucosal dissection with continuous warfarin or 1-day withdrawal of direct oral anticoagulants. J Gastroenterol Hepatol. 39(12):2760-2766, 2024　Dec. (IF=3.4)

 

29. Ito H, Yokoyama Y, Kyo S, Mandai M, Kosaka K, Kobayashi H, Miyagi E, Onuki M, Matsumoto K, Matsumura N, Umemura K, Ishikawa H, Isaka K. Interim analysis of robot-assisted radical hysterectomy in Japan: a multicenter, prospective interventional single-arm clinical trial. BMC Cancer. 24(1):1360, 2024　Nov. (IF=3.4)

 

30. Tomita Y, Yoshida N, Ishikawa H, Otani T, Kobayashi R, Hashimoto H, Hirose R, Dohi O, Inoue K, Morinaga Y, Itoh Y. Prevalence of gastric cancer following colorectal endoscopic submucosal dissection for lesions more than 20 mm: A retrospective analysis. DEN Open. 5(1):e70042, 2024　Dec. (IF=1.5)

 

31. 武藤倫弘、宮本真吾、藤井 元。大腸がんの一次予防（化学予防）はどこまで進んだか：アスピリンを用いたハイリスク・ストラテジー。日消がん検診誌62(4),367-373, 2024.

 

32. 今岡 達彦, 鱧屋 隆博, 柳原 啓見, 森岡 孝満, 臺野 和広, 飯塚 大輔, 大内 則幸. 量子ハンドブック（第２節 生体ナノ量子センサによるがん研究・診断技術の開発）. エヌ・ティー・エス, 2024

 

33. 竹内洋司, 中平博子, 田中久美子, 高山哲治, 石川秀樹.【IV：小腸［治療］】家族性大腸腺腫症における多発小腸ポリープ治療のストラテジー. 消化器内視鏡　特集『スキルアップ内視鏡診療』東京医学社 (2024年10月23日発売),　36，13，2024.

 

34. 石川秀樹. 部会活動の発展と未来. 「遺伝性腫瘍」30 周年記念特集号 一般社団法人日本遺伝性腫瘍学会  24, supplement: 45-47, 2024.

 

35. 石川秀樹.　主題研究1. 家族性大腸腺腫症およびLynch症候群に対する内視鏡治療後サーベイランス. 胃と腸 59, 6: 863-868, 2024.

 

36. 石川秀樹, 山本元久. 特集：IgG4関連疾患－診断と治療の最近の考え方 IgG4関連疾患患者レジストリとその活用. 日本臨床　82, 3:432-437, 2024.

 

37. 竹内洋司, 上田智也, 三宅宗彰, 高田和典, 栗林志行, 石川秀樹, 浦岡俊夫.【各論：D　消化管ポリポーシスと類似ポリープ】家族性大腸ポリポーシス（FAP）に伴う病変：乳頭部腺腫・癌. 消化器内視鏡　特集『十二指腸・小腸アトラス』. 36, 4;536-537, 2024.

 

38. 石川秀樹. 家族性大腸腺腫症に対する新しい治療法. Medical Practice《連載；One Point Advice》. 41, 10, 1589, 2024.

 

39. 竹内洋司, 中平博子, 田中久美子, 高山哲治, 石川秀樹. 家族性大腸腺腫症の（十二指腸を含む）小腸病変に対する内視鏡治療. 臨牀消化器内科. 39, 12, 2024.

 

40. 十倉淳紀, 千野晶子, 小林望, 大圃研, 竹内洋司, 斎藤彰一, 山田真善, 辻陽介, 堀田欣一, 原田馨太, 池松弘朗, 高取祐作, 浦岡俊夫, 村上敬, 辻重継, 片桐敦, 堀伸一郎, 道田知樹, 鈴木拓人, 福澤誠克, 桐山真典, 深瀬和利, 村上義孝, 石川秀樹, 斎藤豊. 大腸ESD長期予後研究(CREATE-J)参加施設における大腸ESDに対するクリニカルパスの現状―多施設共同（20施設）アンケート調査―. 日本消化器内視鏡学会雑誌. 2024, 66, 1, 89-98, 2024

 

2023年

1. Maeda-Minami A, Takagi M, Mano Y,Ishikawa H, Matsuyama Y, Mutoh M. Association between statins and incidence of cancer in patients with dyslipidemia using large-scale health insurance claims data. Cancer Prev Res (Phila). 2023 Jan 4;16(1):37-45. (IF-2.9)

 

2. Yoshida T, Koyama T, Ishimaru T, Minoura A, Mutoh M, Tabuchi T. Fear of COVID-19 among Japanese workers and exacerbation of chronic pain: a nationwide cross-sectional study. J Occup Environ Med. 2023 Mar 1;65(3):e134-e140. (IF-2.3)

 

3. Ishikawa H, Yamada M, Sato Y, Tanaka S, Chino A, Tajika M, Doyama H, Takayama T, Ohda Y, Horimatsu T, Sano Y, Tanakaya K, Ikematsu H, Saida Y, Ishida H, Takeuchi Y, Kashida H, Kiriyama S, Hori S, Lee K, Tashiro J, Kobayashi N, Nakajima T, Suzuki S, Mutoh M, and J-FAPP Study III Group.Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): A multicenter prospective interventional study. Endoscopy. 2023 Apr;55(4):344-352. (IF-11.5)

 

4. Imai T, Naruse M, Machida Y, Fujii G, Mutoh M, Ochiai M, Takahashi M, Nakagama H. Feeding a high-fat diet for a limited duration increases cancer incidence in a breast cancer model. Nutr Cancer. 2023;75(2):713-725. (IF-2.7)

 

5. Dohi O, Ono S, Kawada K, Kitamura S, Hatta W, Hori S, Kanzaki H, Murao T, Yagi N, Sasaki F, Hashiguchi K, Oka S, Katada K, Shimoda R, Mizukami K, Suehiro M, Takeuchi T, Katsuki S, Tsuda M, Naito Y, Kawano T, Haruma K,Ishikawa H, Mori K, Kato M, LCI-FIND TRIAL Group. Linked color imaging provides enhanced visibility with a high color difference in upper gastrointestinal neoplasms. J Gastroenterol Hepatol. 38,1:79-86, 2023.

 

6. Suzuki S, Aniwan S, Chiu HM, Laohavichitra K, Chirapongsathorn S, Yamamura T, Kuo CY, Yoshida N, Ang TL, Takezawa T, Rerknimitr R, Ishikawa H, Gotoda T, ATLAS Trial Group. Linked-color imaging detects more colorectal adenoma and serrated lesions: an international randomized controlled trial. Clin Gastroenterol Hepatol. 21,6:1493-1502.e4, 2023. (IF-11.6)

 

7. Takeuchi Y, Hamada K, Nakahira H, Shimamoto Y, Sakurai H, Tani Y, Shichijo S, Maekawa A, Kanesaka T, Yamamoto S, Higashino K, Fujisawa F, Ezoe Y, Ishikawa H, Mutoh M, Uedo N, Nojima M, Ishihara R. Efficacy and safety of intensive endoscopic intervention for multiple duodenal adenomas in patients with familial adenomatous polyposis: A prospective cohort study. Endoscopy 2023 Jun;55(6):515-523. (IF-11.5)

 

8. Zhou T, Ando T, Kudo A, Sato M, Miyoshi N, Mutoh M, Ishikawa H, Wakabayashi K, Watanabe K. Screening method toward ClbP-specific inhibitors. Genes Environ. 2023 Feb 16;45(1):8. (IF-2.7)

 

9. Yamamoto H, Sakamoto H, Kumagai H, Abe T, Ishiguto S, Uchida K, Kawasaki Y, Saida Y, Sano Y, Takwuchi Y, Tajika M, Nakajima T, Banno K, Funasaka Y, Hori S, Yamaguchi T, Yoshida T, Ishikawa H, Iwama T, Okazaki Y, Saito Y, Matsuura N, Mutoh M, Tomita N, Akiyama T, Yamamoto T, Ishida H, Nakayama Y. Clinical Guidelines for Diagnosis and Management of Peutz-Jeghers Syndrome in Children and Adults. Digestion. 2023 Apr 13;1-13. (IF-3.0)

 

10. Matsumoto T, Umeno J, Jimbo K, Arai M, Iwama I, Kashida H, Kudo T, Koizumi K, Sato Y, Sekine S, Tanaka S, Tanakaya K, Tanuma K Hirata K, Fukahori S, Esaki M, Ishikawa H, Iwama T, Okazaki Y, Saito Y, Matsuura N, Mutoh M, Tomita N, Akiyama T, Yamamoto T, Ishida H, Nakayama Y. Clinical Guidelines for Diagnosis and Management of Juvenile Polyposis Syndrome in Children and Adults. J Anus Rectum Colon. 2023 Apr 25;7(2):115-125. (IF-1.4)

 

11. Sugiura S, Yamahira S, Tamura M, Shin K, Shibuta M, Satoh T, Matsuzawa Y, Fujii G, Yanagawa F, Mutoh M, Yanagisawa M, Kato R, Matsui H. Automated cell isolation from photodegradable hydrogel based on fluorescence image analysis. Biotechnol Bioeng. 2023 Jun;120(6):1492-1505. (IF-3.5)

 

12. Nakao-Ise Y, Narita T, Miyamoto S, Watanabe M, Tanaka T, Sowa Y, Iizumi Y, Masuda M, Fujii G, Hirai Y, Nakao T, Takakura H, Mutoh M. Induction of MYCN-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist. J Clin Biochem Nutr. 2023 Nov;73(3):191-197. (IF-2.4)

 

13. Inoki K, Takamaru H, Furuhashi H, Kishida Y, Shimodate Y, Sumida Y, Hosotani K, Ueyama H, Furumoto Y, Hashimoto S, Takeuchi Y, Ichijima R, Yoshizawa Y, Suzuki T, Minoda Y, Mizukami K, Matsumura T, Kasai T, Yamamura T, Ohnita K, Hara K, Esaki M, Katagiri A, Ishikawa H, Gotoda T. Management of colorectal high-grade dysplasia or cancer resected by cold snare polypectomy: a multicentre exploratory study. J Gastroenterol. 58,6:554-564, 2023. (IF-6.9)

 

14. Kondo T, Kanai M, Matsubara J, Yamaguchi D, Ura T, Kou T, Itani T, Nomura M, Funakoshi T, Masui T, Yokoyama A, Doi K, Tamaoki M, Yoshimura M, Uza N, Yamada T, Minamiguchi S, Matsumoto S, Ishikawa H, Muto M. Association between homologous recombination gene variants and efficacy of oxaliplatin-based chemotherapy in advanced pancreatic cancer: prospective multicenter observational study. Med Oncol. 40,5:144, 2023. (IF-2.8)

 

15. Shimamoto Y, Takeuchi Y, Ishiguro S, Nakatsuka S, Yunokizaki H, Ezoe Y, Matsuno K, Nakahira H, Shichijo S, Maekawa A, Kanesaka T, Yamamoto S, Higashino K, Uedo N, Ishihara R, Ishikawa H. Feasibility of underwater endoscopic mucosal resection for endoscopic management of gastric neoplasms in patients with familial adenomatous polyposis. Surg Endosc. 37,9:6877-6884, 2023. (IF-2.4)

 

16. Takayama T, Muguruma N, Igarashi M, Ohsumi S, Oka S, Kakuta F, Kubo Y, Kumagai H, Sasaki M, Sugai T, Sugano K, Takeda Y, Doyama H, Banno K, Fukahori S, Furukawa Y, Horimatsu T, Ishikawa H, Iwama T, Okazaki Y, Saito Y, Matsuura N, Mutoh M, Tomita N, Akiyama T, Yamamoto T, Ishida H, Nakayama Y. Clinical Guidelines for Diagnosis and Management of Cowden/PHTS Syndrome in Children and Adults. J Anus Rectum Colon. 2023 Oct 25;7(4):284-300. (IF-1.4)

 

17. Yoshida N, Maeda-Minami A, Ishikawa H, Mutoh M, Kanno Y, Tomita Y, Hirose R, Dohi O, Itoh Y, Mano Y. Analysis of the development of gastric cancer after resecting colorectal lesions using large-scale health insurance claims data. J Gastroenterol. 2023 Nov;58(11):1105-1113. (IF-6.9)

 

18. Shimamoto Y, Takeuchi Y, Ishiguro S, Nakatsuka S-I, Yunokizaki H, Ezoe Y, Nakajima T, Tanka K, Ishihara R, Takayama T, Yoshida T, Sugano K, Mutoh M, Ishikawa H. Genotype–phenotype correlation for extracolonic aggressive phenotypes in patients with familial adenomatous polyposis. Cancer Sci. 2023 Dec;114(12):4596-4606. (IF-4.5)

 

19. Katada C, Yokoyama T, Mure K, Doyama H, Nakanishi H, Shimizu Y, Yamamoto K, Furue Y, Tamaoki M, Koike T, Kawahara Y, Kiyokawa H, Konno M, Yokoyama A, Ohashi S, Ishikawa H, Yokoyama A, Muto M. Risk factors for the development of second primary esophageal squamous-cell carcinoma after endoscopic resection for esophageal squamous-cell carcinoma according to genetic polymorphisms related to alcohol and nicotine metabolism. Jpn J Clin Oncol. 53,9：774-780, 2023. (IF-1.9)

 

20. Katada C, Yokoyama T, Yano T, Suzuki H, Furue Y, Yamamoto K, Doyama H, Koike T, Tamaoki M, Kawata N, Hirao M, Kawahara Y, Ogata T, Katagiri A, Yamanouchi T, Kiyokawa H, Kawakubo H, Konno M, Yokoyama A, Ohashi S, Kondo Y, Kishimoto Y, Kano K, Mure K, Ishikawa H, Yokoyama A, Muto M. Alcohol consumption, multiple Lugol-voiding lesions, and field cancerization. DEN Open. 4,1:e261, 2023. (IF-1.4)

 

21. Hirao M, Katada C, Yokoyama T, Yano T, Suzuki H, Furue Y, Yamamoto K, Doyama H, Koike T, Tamaoki M, Kawata N, Kawahara Y, Katagiri A, Ogata T, Yamanouchi T, Kiyokawa H, Kawakubo H, Konno M, Ishikawa H, Yokoyama A, Muto M. Metachronous primary gastric cancer after endoscopic resection in patients with esophageal squamous cell carcinoma. Gastric Cancer. 26,6:988-1001, 2023. (IF-6.0)

 

22. Saito E, Mutoh M, Ishikawa H, Kamo K, Fukui K, Hori M, Ito Y, Chen Y, Sigel B, Sekiguchi M, Hemmi O, Katanoda K. Cost-effectiveness of preventive aspirin use and intensive downstaging polypectomy in patients with familial adenomatous polyposis: a microsimulation modeling study. Cancer Med. 2023 Sep;12(18):19137-19148. (IF-2.9)

 

23. Masuda M, Horinaka M, Yasuda S, Morita M, Nishimoto E, Ishikawa H, Mutoh M, Sakai T.  Discovery of cancer-preventive juices reactivating RB functions. Environ Health Prev Med. 2023:28:54. (IF-4.7)

 

24. Itoh Y, Zhan P, Tojo T, Jaikhan P, Ota Y, Suzuki M, Li Y, Hui Z, Moriyama Y, Takada Y, Yamashita Y, Oba M, Uchida S, Masuda M, Ito S, Sowa Y, Sakai T, Suzuki T. Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation. J Med Chem 66:15171-15188, 2023. (IF= 6.8)

 

25. Nakahira H, Takeuchi Y, Shimamoto Y, Ishiguro S, Yunokizaki H, Ezoe Y, Fujisawa F, Ishihara R, Takayama T, Yoshida T, Mutoh M, Ishikawa H. Progression of duodenal neoplasia to advanced adenoma in patients with familial adenomatous polyposis. Hered Cancer Clin Pract. 2023 Nov 27;21(1):25. (IF-2.0)

 

26. Maeda-Minami A, Nishikawa T, Ishikawa H, Mutoh M, Akimoto K, Matsuyama Y, Mano Y, Uemura H. Association of PSA variability with prostate cancer development using large-scale medical information data: A retrospective cohort study. Genes Environ. 2023 Oct 17;45(1):25. (IF-2.7)

 

27. Nakai K, Lin H, Yamano S, Tanaka S, Kitamoto S, Saitoh H, Sakuma K, Kurauchi J, Akter E, Konno M, Ishibashi K, Kamata R, Ohashi A, Koseki J, Takahashi H, Yokoyama H, Shiraki Y, Enomoto A, Abe S, Hayakawa Y, Ushiku T, Mutoh M, Fujita Y, Kon S. Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway. Nat Commun. 2023 Nov 3;14(1):7048. (IF-14.7)

 

28. Maeda-Minami A, Nishikawa T,Ishikawa H, Mutoh M, Makishima Y, Matsuyama Y, Akimoto K, Mano Y, Uemura H. Angiotensin II receptor blockers cause changes in prostate-specific antigen levels: A retrospective cohort study. Anticancer Res. 2023 Dec;43(12):5629-5636. (IF-2.4)

 

29. Hamoya T, Tomono S, Miyamoto S, Fujii G, Wakabayashi K, Mutoh M. Theoretical basis validation and oxidative stress markers for cancer prevention clinical trials of aspirin.  Sci Rep. 2023 Dec 11;13(1):21883. (IF-3.8)

 

30. 山本裕子, 山本容子, 山田親代, 室田昌子, 成本迅, 武藤倫弘. 看護師のレジリエンスを高める介入研究に関する文献検討.京都府立医科大学看護学科紀要33, 29-37, 2023.

 

31. 武藤倫弘, 宮本真吾, 藤井 元. 大腸がんの化学予防：アスピリンを用いたハイリスク・ストラテジー. Precision Medicine 6(4), 35-38, 2023.

32. 渡邉元樹. コーヒー成分の大腸がん予防のメカニズムについて. 食と医療 27号: 22-31, 2023.

 

33. 石川秀樹. 大腸腫瘍の内視鏡治療後の適切なサーベイランス法は？. 消化器内科診療Controversy, 59:304-308, 2023.

 

34. 石川秀樹. 家族性大腸線種症. MUTYH関連ポリポーシス Familial adenomatous polyposis, MUTYH-associated polyposis. 日本臨牀2023年5月増刊「最新臨床大腸癌学」. 81, Suppl 5: 420-425, 2023.

 

35. 石川秀樹, 竹内洋司. 遺伝性消化管疾患を考える 家族性大腸線種症の診断・治療の最前線. 胃と腸. 58, 12: 1602-1608, 2023.

 

36. 石川秀樹, 山本元久. 特集：IgG4関連疾患 －診断と治療の最近の考え方　IgG4関連疾患患者レジストリとその活用Registry for IgG4-related disease. 日本臨床2023年5月増刊「最新臨床大腸癌学」. 81, Suppl 5: P432-437, 2023.

 

37. 石川秀樹. 家族性大腸腺腫症患者における腸管手術回避マネージメントへの挑戦―内視鏡介入試験および低用量アスピリンによる薬物療法の進歩―. 日本消化器内視鏡学会誌 65, 11: 2275-2282, 2023.

 

2022年

38. Terasaki M, Ono S, Hashimoto S, Kubota A, Kojima H, Ohta T, Tanaka T, Maeda H, Miyashita K, Mutoh M. Suppression of C-C chemokine receptor 1 is a key regulation for colon cancer chemoprevention in AOM/DSS mice by fucoxanthin. J Nutr Biochem. 2022 Jan;99:108871.doi: 10.1016/j.jnutbio.2021.108871. (IF=5.6)

 

39. Iwasaki M, Kanehara R, Yamaji T, Katagiri R, Mutoh M, Tsunematsu Y, Sato M, Watanabe K, Hosomi K, Kakugawa Y, Ikematsu Hi, Hotta K, Kunisawa J, Wakabayashi K, Matsuda T. Association of Escherichia coli containing polyketide synthase in the gut microbiota with colorectal neoplasia in Japan. Cancer Sci. 2022 Jan;113(1):277-286.doi: 10.1111/cas.15196. (IF= 5.7) 

 

40. Takakura H, Horinaka M, Imai A, Aono Y, Nakao T, Miyamoto S, Iizumi Y, Watanabe M, Narita T, Ishikawa H, Mutoh M, Sakai T. Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells. J Clin Biochem Nutr. 2022 Mar;70(2):93-102. doi: 10.3164/jcbn.21-74. (IF= 2.4) 

 

41. Narita T, Tsunematsu Y, Miyoshi N, Komiya M, Hamoya T, Fujii G, Yoshikawa Y, Sato M, Kawanishi M, Sugimura H, Iwashita Y, Totsuka Y, Terasaki M, Watanabe K, Wakabayashi K, Mutoh M. Induction of DNA damage in mouse colorectum by administration of colibactin-producing Escherichia coli, isolated from a patient with colorectal cancer. In Vivo. 2022 Mar-Apr;36(2):628-634. doi: 10.21873/invivo.12746. (IF= 2.3)

 

42. Sakaguchi T, Satoi S, Hashimoto D, Yamamoto T, Yamaki S, Hirooka S, Ishida M, Ikeura T, Inoue K, Naganuma M, Ishikawa H, Sekimoto M. High tumor budding predicts a poor prognosis in resected duodenal adenocarcinoma. Surg Today. 2022 Jun;52(6):931-940.  doi: 10.1007/s00595-021-02433-z. (IF= 2.5) 

 

43. Yoshida N, Ishikawa H, Eguchi H, Okazaki Y, Hirose R, Inoue K, Dohi O, Itoh Y, Mutoh M, Ishiguro S, Ishida H. The promotion effects of smoking for polyp development in monozygotic twins with atypical colorectal polyposis. Case Rep Gastroenterol. 2022 Jun 13;16(2):375-381. doi: 10.1159/000524944. (IF= -)

 

44. Yokoyama R, Kushibiki A, Yamada S, Kubota A, Kojima H, Ohta T, Hamada J, Maeda H, Mutoh M, Terasaki M. Requirement of CLIC4 expression in human colorectal cancer cells for sensitivity to growth inhibition by fucoxanthinol. Cancer Genomics Proteomics. 2022 Jul-Aug;19(4):428-444. doi: 10.21873/cgp.20330. (IF= -)

 

45. Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Matsuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T. Chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5. PNAS Nexus, 2022 May 1(2): pgac059. doi.org/10.1093/pnasnexus/pgac059(IF= -)

 

46. Takakura H, Nakao T, Narita T, Horinaka M, Nakao-Ise Y, Yamamoto T, Iizumi Y, Watanabe M, Sowa Y, Oda K, Mori N, Sakai T, Mutoh M. Citrus limon L.-derived nanovesicles show an inhibitory effect on cell growth in p53-inactivated colorectal cancer cells via the macropinocytosis pathway. Biomedicines 10 (6): 1352. doi.org/10.3390/biomedicines10061352. (IF= 4.7)

 

47. Terasaki M, Murase W, Kamakura Y, Kawakami S, Kubota A, Kojima H, Ohta T, Tanaka T, Maeda H, Miyashita K, Mutoh M. Biscuit containing fucoxanthin prevents colorectal carcinogenesis in azoxymethane/dextran sodium sulfate-induced mice. Nutrition and Cancer 2022 74(10). doi.org/10.1080/01635581.2022.2086703(IF= 2.9)

 

48. Imai A, Horinaka M, Aono Y, Iizumi Y, Takakura H, Ono H, Yasuda S, Taniguchi K, Nishimoto E, Ishikawa H, Mutoh M, Sakai T. Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells. Biochem Biophys Res Commun. 2022 Nov 5;628:110-115. doi: 10.1016/j.bbrc.2022.08.082. (IF= 3.58)

 

49. Yoshida N, Ishikawa H, Otani T, Mutoh M, Goto C, Matsuda T, Takeuchi Y, Sano Y, Suzuki S, Itoh Y, and J-CAPP Study group. Aspirin interaction in the recurrence of colorectal adenomas affected by blood biochemistry and nutritional intake. Cancer Prev Res. 2022 Dec 1;15(12): 837-846.doi: 10.1158/1940-6207.CAPR-22-0144. (IF= 3.3)

 

50. Wada H, Sato Y, Fujimoto S, Okamoto K, Bando M, Kawaguchi T, Miyamoto H, Muguruma N, Horimoto K, Matsuzawa Y, Mutoh M, Takayama T. Resveratrol inhibits development of colorectal adenoma via suppression of LEF1; Comprehensive analysis with connectivity map. Cancer Sci. 2022 Dec;113(12):4374-4384. doi: 10.1111/cas.15576. (IF= 5.7) 

 

51. Haruma K, Kato M, Kawada K, Murao T, Ono S, Suehiro M, Hori S, Sasaki F, Koike T, Kitamura S, Dohi O, Kanzaki H, Yagi N, Hashiguchi K, Oka S, Katada K, Shimoda R, Mizukami K, Takeuchi T, Katsuki S, Tsuda M, Naito Y, Kawano T, Mori K, Ishikawa H. Diagnostic ability of linked color imaging in ultraslim endoscopy to identify neoplastic lesions in the upper gastrointestinal tract. Endosc Int Open. 2022, 10, 1, E88-E95, doi: 10.1055/a-1723-2635. (IF= 2.6)

 

52. Nakajima T, Sakamoto T, Hori S, Yamada S, Ikematsu H, Harada K, Chiu HM, Kiriyama S, Michida T, Hotta K, Sakamoto N, Abe T, Chino A, Fukuzawa M, Kobayashi N, Fukase K, Matsuda T, Murakami Y, Ishikawa H, Saito Y. Optimal surveillance interval after piecemeal endoscopic mucosal resection for large colorectal neoplasia: a multicenter randomized controlled trial. Surgical Endoscopy. 2022, 36, 1, 515-25, doi: 10.1007/s00464-021-08311-6. (IF= 3.1)

 

53. Satoki S, Takeuchi Y, Shimodate Y, Yamashina T, Yamasaki T, Hayashi T, Hirasawa K, Fukunaga S, Yamaguchi S, Asai S, Kawamura T, Fukata N, Yamamoto M, Teramoto A, Kinjo Y, Matsuno K, Kinjo T, Sano Y, Iwatsubo T, Nagaike K, Matsumoto M, Hoki N, Kawamura I, Shimokawa T, Uedo N, Ishikawa H, Tanaka K, Kitano M, Kansai Endoscopic Device Selection Conference in Kansai Research Group. Performance of perioperative antibiotics against post-endoscopic submucosal dissection coagulation syndrome: a multicenter randomized controlled trial. Gastrointest Endosc. 2022, 95, 2, 349-59, doi: 10.1016/j.gie.2021.08.025. (IF= 7.7)

 

54. Hashimoto D, Satoi S, Ishikawa H, Kodera Y, Kamei K, Hirano S, Fujii T, Uemura K, Tsuchida A, Yamada S, Yamamoto T, Hirota K, Sekimoto M. Efficacy of active hexose correlated compound on survival of patients with resectable/borderline resectable pancreatic cancer: a study protocol for a double-blind randomized phase II study. Trials. 2022, 23, 1, 135, doi: 10.1186/s13063-021-05934-x. (IF= 2.5)

 

55. Teramae S, Muguruma N, Okamoto K, Oseto K, Nishikawa R, Tanoue T, Hirata K, Yanai S, Matsumoto T, Shimizu S, Miwa J, Sasaki Y, Yashima K, Ohnuma H, Sato Y, Kitayama Y, Ohda Y, Yamauchi A, Sanomura Y, Tanaka K, Kubo Y, Ishikawa H, Bando Y, Sonoda T, Takayama T. Cancer risk and genotype-phenotype correlation in Japanese patients with Cowden syndrome. Int J Clin Oncol. 2022;27(4):639-647.  doi: 10.1007/s10147-022-02116-w. (IF=3.3) 

 

56. Tanaka K, Sato Y, Ishikawa H, Muguruma N, Teramae S, Takeuchi Y, Mitsui Y, Okamoto K, Miyamoto H, Bando Y, Sonoda T, Omiya N, Mutoh M, Takayama T. Small Intestinal Involvement and Genotype-Phenotype Correlation in Familial Adenomatous Polyposis., Tech Innov Gastrointest Endosc. 24 (1) 26-34, 2022.doi: https://doi.org/10.1016/j.tige.2021.10.001. (IF= 2.4)

 

57. Ohata K, Kobayashi N, Sakai E, Takeuchi Y, Chino A, Takamaru H, Kodashima S, Hotta K, Harada K, Ikematsu H, Uraoka T, Murakami T, Tsuji S, Abe T, Katagiri A, Hori S, Michida T, Suzuki T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Saito Y. Long-term Outcomes After Endoscopic Submucosal Dissection for Large Colorectal Epithelial Neoplasms: A Prospective, Multicenter, Cohort Trial From Japan. Gastroenterology. 2022;163(5): 1423-1434.e2. (IF= 29.4)

 

58. Mure K, Ishikawa H, Mutoh M, Horinaka M, Otani T, Suzuki S, Wakabayashi K, Sakai T, J-FAPP Study IV group. Efficacy of low-dose aspirin in colorectal cancer risk prevention is dependent on ADH1B and ALDH2 genotype in Japanese familial adenomatous polyposis patients. Cancer Res Commun. 2022;2(6): 483-488.(IF=-)

 

59. Suzuki S, Aniwan S, Chiu, H-M Laohavichitra K, Chirapongsathorn S, Yamamura T, Kuo C-Y, Yoshida N, Leong Ang T, Takezawa T, Rerknimitr R, Ishikawa H, Gotoda T; ATLAS Trial Group. Linked-Color Imaging Detects More Colorectal Adenoma and Serrated Lesions: An International Randomized Controlled Trial. Clin Gastroenterol Hepatol. 2022;21(6):1493-1502.e4. (IF= 5.29)

 

60. Yamamoto Y, Yoshida N, Yano T, Horimatsu T, Uedo N, Kawata N, Kanzaki H, Hori S, Yao K, Abe S, Katada  C, Yokoi C, Ohata K, Doyama H, Yoshimura K, Ishikawa H, Muto M. Assessment of outcomes from 1-year surveillance after detection of early gastric cancer among patients at high risk in Japan. JAMA Netw Open. 2022;5(8): e2227667. (IF= 13.8)

 

61. Ogawa-Ochiai K, Ishikawa H, Nishimura H, Okajima M, Iinuma Y, Ito M. Clinical and epidemiological features of healthcare workers after a coronavirus disease 2019 cluster infection in Japan and the effects of Kampo formulas-Hochuekkito and Kakkonto: A retrospective cohort study. Medicine (Baltimore). 2022;101(280): e29748. (IF= 1.6)

 

62. Sakaguchi T, Satoi S, Hashimoto D, Yamamoto T, Yamaki S, Hirooka S, Ishida M, Ikeura T, Inoue K, Naganuma M, Ishikawa H, Sekimoto M. High tumor budding predicts a poor prognosis in resected duodenal adenocarcinoma. Surg Today. 2022;52(6): 931-940. (IF= 2.5)

 

63. Sekiguchi M, Hotta K, Takeuchi Y, Tanaka S, Yamamoto H, Ikematsu H, Harada K, Uraoka T, Hisabe T, Sano Y, Kondo H, Horimatsu T, Kikuchi H, Kawamura T, Nagata S, Yamamoto K, Tajika M, Tsuji S, Kusaka T, Okuyama Y, Yoshida N, Moriyama T, Hasebe A, So S, Kobara H, Kashida H, Miyanaga R, Kato S, Hayashi Y, Sada, M Fukuzawa M, Kato H, Takayama T, Konishi J, Matsushita H, Narasaka T, Ohata K, Togashi K, Nakamura H, Moriichi K, Oda Y, Kanda N, Kuwai T, Terai S, Sanomura M, Kitamura S, Miyamoto H, Kiriyama S, Mizuno C, Saito Y, Sekine S, Ito S, Nakahira H, Oka S, Hayashi Y, Yoshimura K, Ishikawa H, Matsuda T; C-NET STUDY Group. Characteristics of colorectal neuroendocrine tumors in patients prospectively enrolled in a Japanese multicenter study: a first report from the C-NET STUDY. J Gastroenterol. 2022;57(8): 547-558. (IF= 6.3)

 

64. Tanigawa T, Takeshima N, Ishikawa H, Nishio S, Usami T, Yamawaki T, Oishi T, Ihira K, Kato H, Goto M, Saito M, Taira Y, Yokoyama M, Shoji T, Kondo E, Mori A, Yokoi T, Iwasa-Inoue N, Hirashima Y, Nagasawa T, Takenaka M, Mikami M, Sugiyama T, Enomoto T. Paclitaxel-carboplatin and bevacizumab combination with maintenance bevacizumab therapy for metastatic, recurrent, and persistent uterine cervical cancer: An open-label multicenter phase II trial (JGOG1079). Gynecol Oncol. 2022;165(3): 413-419. (IF= 4.7)

 

65. Shimohara Y, Urabe Y, Oka S, Hisabe T, Yamada A, Matsushita H, Kato B, Sakamoto H, Horii J, Watanabe D, Eda H, Nakamura F, Chino A, Yamamoto H, Takayama T, Matsumoto T, Ishikawa H, Tanaka S. Clinicopathological characteristics of colorectal serrated polyposis syndrome (SPS): results of a multicenter study by the SPS Study Group in Japan. J Gastroenterol. 57, 4, 300-308, 2022. (IF= 6.3)

 

66. Kobayashi N, Takeuchi Y, Ohata K, Igarashi M, Yamada M, Kodashima S, Hotta K, Harada K, Ikematsu H, Uraoka T, Sakamato N, Doyama H, Abe T, Katagiri A, Hori S, Michida T, Yamaguchi T, Fukuzawa M, Kiriyama S, Fukase K, Murakami Y, Ishikawa H, Saito Y. Outcomes of endoscopic submucosal dissection for colorectal neoplasms: Prospective, multicenter, cohort trial. Dig Endosc. 2022;34(5):1042-1051. (IF= 0.7)

 

67. Muto M, Katada C, Yokoyama T, Yano T, Oda I, Ezoe Y, Tanabe S, Shimizu Y, Doyama H, Koike T, Takizawa K, Hirao M, Okada H, Ogata T, Katagiri A, Yamanouchi T, Matsuo Y, Kawakubo H, Omori T, Kobayashi N, Shimoda T, Ochiai A, Ishikawa H, Baba K, Yokoyama A, Ohashi S, Yokoyama A; Japan Esophageal Cohort Study Group. Field effect of alcohol, cigarette smoking, and their cessation on the development of multiple dysplastic lesions and squamous cell carcinoma: A Long-term Multicenter Cohort Study. GastroHep Advances. 2022;1(2):265-276. (IF= -)

 

68. Shichijo S, Takeuchi Y, Shimodate Y, Yamashina T, Yamasaki T, Hayashi T, Hirasawa K, Fukunaga S, Yamaguchi S, Asai S, Kawamura T, Fukata N, Yamamoto M, Teramoto A, Kinjo Y, Matsuno K, Kinjo, T Sano Y, Iwatsubo T, Nagaike, K Matsumoto M, Hoki N, Kawamura I, Shimokawa T, Uedo N, Ishikawa H, Tanaka K, Kitano M; Kansai Endoscopic Device Selection Conference in Kansai Research Group. Performance of perioperative antibiotics against post-endoscopic submucosal dissection coagulation syndrome: a multicenter randomized controlled trial. Gastrointest Endosc. 2022;95(2): 349-359. (IF= 7.7)

 

69. Ota Y, Itoh Y, Kurohara T, Singh R, Elboray EE, Hu C, Zamani F, Mukherjee A, Takada Y, Yamashita Y, Morita M, Horinaka M, Sowa Y, Masuda M, Sakai T, Suzuki T. Cancer-Cell-Selective Targeting by Arylcyclopropylamine–Vorinostat Conjugates. ACS Med. Chem. Lett. 2022, 13, 10, 1568–1573. (IF= 4.6)

 

70. Iizumi Y, Sowa Y, Goi W, Aono Y, Watanabe M, Kurumida Y, Kameda T, Akaji K, Kitagawa M, Sakai T. Stabilization of CDK6 by ribosomal protein uS7, a target protein of the natural product fucoxanthinol. Commun Biol. 5(1):564, 2022.(IF= 5.9)

 

71. 藏滿保宏、武藤倫弘、寺崎　将、岡田　太。シンポジウム6『がん予防研究と今後の展開』の企画報告。 電気泳動　2022；66 Doi:10.2198/electroph.66.1．

 

72. 成田　匠、宮本真吾、武藤倫弘。抗酸化制御能を有する食品成分による老化制御。食と医療（特集：老化と栄養）, 22-29, 2022．

 

2021年

73. Yokoyama　R, Kojima H, Takai R, OhtaT, Maeda H, Miyashita K, Mutoh M, Terasaki M. Effects of CLIC4 on fucoxanthinol-induced apoptosis in human colorectal cancer cells. Nutr Cancer. 73(5):889-898, 2021.doi: 10.1080/01635581.2020.1779760. (IF= 2.805)

 

74. Hamoya T, Fujii G, Iizumi Y, Narita T, Komiya M, Matsuzawa Y, Miki K, Kondo T, Kishimoto S, Watanabe K, Wakabayashi K, Sakai T, Toshima J, Mutoh M. Artesunate Inhibits Intestinal Tumorigenesis through Inhibiting Wnt Signaling. Carcinogenesis.  2021 Feb 11;42(1):148-158. doi: 10.1093/carcin/bgaa084. (IF= 4.944)

 

75. Terasaki M. Uehara O, Ogasa S, Sano T, Kubota A, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M. Alteration of fecal microbiota by fucoxanthin results in prevention of colorectal cancer in AOM/DSS mice. Carcinogenesis.2021 Feb25;42(2):210-219. doi:10.1093/carcin/bgaa100. (IF= 4.944)

 

76. Terasaki M,　Takahashi S, Nishimura R, Kubota A, Kojima H, Ohta T, Hamada J, Kuramitsu Y, Maeda H, Miyashita K, Takahashi M, Mutoh M. A marine carotenoid of fucoxanthinol accelerates the growth of human pancreatic cancer PANC-1 cells. Nutr Cancer. 2021 Feb 16;1-16. doi: 10.1080/01635581.2020.1863994. (IF= 2.805)

 

77. Ishikawa H, Mutoh M, Sato Y, Doyama H, Tajika M, Tanaka S, Horimatsu T, Takeuchi Y, Kashida H, Tashiro J, Ezoe Y, Nakajima T, Ikematsu, H Hori S, Suzuki S, Otani T, Takayama T, Ohda Y, Mure K, Wakabayashi K, Sakai T. Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial. Lancet Gastroenterol Hepatol. 2021 Jun;6(6):474-481. doi: 10.1016/S2468-1253(21)00018-2. (IF= 45.042)

 

78. Watanabe M, Yamada Y, Kurumida Y, Kameda T, Sukeno M, Iizuka-OhashiM, Sowa Y, Iizumi Y, Takakura H, Miyamoto S, Sakai T, Mutoh M. Rabdosianone I, a bitter diterpene from an oriental herb, suppresses thymidylate synthase expression by directly binding to ANT2 andPHB2.Cancers(Basel).2021Feb26;13(5):982. doi:10.3390/cancers13050982. (IF= 6.575)

 

79. Terasaki M, Inoue T, Murase W, Kubota A, Kojima H, Kojoma M, Ohta T, Maeda H, Miyashita K, Mutoh M, Takahashi M. A fucoxanthinol induces apoptosis in a pancreatic intraepithelial neoplasia cell.　Cancer Genomics Proteomics. 2021 Mar-Apr;18(2):133-146. doi: 10.21873/cgp.20248. (IF= 4.069)

 

80. Terasaki M, Hamoya T, Kubota A, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M. Fucoxanthin prevents colorectal canecr development in dextran sodium sulfate-treated Apc Min/+ mice. Anticancer Res. 2021Mar;41(3):1299-1305. doi: 10.21873/anticanres.14887.(IF= 2.48)

 

81. Yoshida N, Mano Y, Matsuda T, Sano Y, Inoue K, Hirose R, Dohi O, Itoh Y, Sobue T, Takeuchi Y, Nakayama T, Mutoh M, Ishikawa H. Complications of colonoscopy in Japan: An analysis using large-scale health insurance claims data. J Gastroenterol Hepatol. 2021 Oct;36(10):2745-2753. doi: 10.1111/jgh.15531.  (IF= 4.369)

 

82. Takahashi M, Hamoya T, Narita T, Fujii G, Totsuka Y, Hagio M, Tashiro K, Komiya M, Mutoh M. Complex modulating effects of dietary calcium intake on obese mice. In Vivo. 2021 Jul-Aug;35(4):2107-2114. doi: 10.21873/invivo.12480. (IF= 2.155)

 

83. Terasaki M, Kubota A, Kojima H, Maeda H, Miyashita K, Kawagoe C, Mutoh M, Tanaka T. Fucoxanthin and colorectal cancer prevention. Cancers (Basel). 2021 May 14;13(10):2379.doi: 10.3390/cancers13102379. (IF= 6.575)

 

84. YWatanabe M, Ishikawa H, Ishiguro S, Mutoh M. Importance of sessile serrated lesions in a patient with familial adenomatous polyposis. Clin J Gastroenterol.2021 Dec;14(6):1667-1670. doi: 10.1007/s12328-021-01498-0. (IF= 3.062)

 

85. Tsunematsu Y, Hosomi K, Kunisawa J, Sato M, Shibuya N, Saito E, Murakami H, Yoshikawa Y, Iwashita Y, Miyoshi N, Mutoh M, Ishikawa H, Sugimura H, Miyachi M, Wakabayashi K, Watanabe K. Mother-to-infant transmission of the carcinogenic colibactin-producing bacteria. BMC Microbiol. 2021 Aug 24;21(1):235. doi: 10.1186/s12866-021-02292-1. (IF= 4.465)

 

86. Yokoyama R, Kubota A, Kojima H, Tanaka T, Mutoh M, Terasaki M. Detection of cells displaying high expression of CLIC4 in tumor tissue of patients with colorectal cancer. In Vivo. Nov-Dec 2021;35(6):3165-3173. doi: 10.21873/invivo.12611. (IF= 2.155)

 

87. Mure K, Tomono S, Mure M, Horinaka M, Mutoh M, Sakai T, Ishikawa H, Wakabayashi K. The combination of cigarette smoking and alcohol drinking synergistically increases reactive carbonyl species in human plasma. Int J Mol Sci. 

    2021 Aug 22;22(16):9043. doi: 10.3390/ijms22169043. (IF= 6.009)

 

88. Murase W, Kamakura Y, Kawakami S, Yasuda A, Wagatsuma M, Kubota A, Kojima H, Ohta T, Takahashi M, Mutoh M, Tanaka T, Maeda H, Miyashita K, Terasaki M. Fucoxanthin prevents pancreatic tumorigenesis in C57BL/6J　mice that received allogenic and orthotopic transplantations of the cancer cells. Int J Mol Sci.  

    2021 Dec 19;22(24):13620. doi: 10.3390/ijms222413620. (IF= 6.009)

 

89. Zhou T, Hirayama Y, Tsunematsu Y, Suzuki N, Tanaka S, Uchiyama N, Goda Y, Yoshikawa Y, Iwashita Y, Sato M, Miyoshi N, Mutoh M, Ishikawa H, Sugimura H, Wakabayashi K, Watanabe K. Isolation of new colibactin Metabolites from wild-type Escherichia coli and In Situ trapping of a mature colibactin derivative. J Am Chem Soc. 2021 Apr 14;143(14):5526-5533. doi: 10.1021/jacs.1c01495. (IF= 16.383)

 

90. Yamazaki H, Shimizu M, Otani T, Mizugaki A, Mure K, Suzuki S, Ishikawa H. Effects of polymorphic cytochrome P450 2A6 genotypes on chemoprevention using daily low-dose aspirin against colorectal tumors in a Japanese cohort: Insights into future personalized treatments. Journal of Pharmaceutical Health Care and Sciences. 2021, 7, 1, 26, doi: 10.1186/s40780-021-00209-8.  (IF= 0.8)

 

91. Tomita N, Ishida H, Tanakaya K, Yamaguchi T, Kumamoto K, Tanaka T,Hinoi T, Miyakura Y, Hasegawa H, Takayama T, Ishikawa H, Nakajima T, Chino A, Shimodaira H, Hirasawa A, Nakayama Y, Sekine S, Tamura K, Akagi K, Kawasaki Y, Kobayashi H, Arai M, Itabashi M, Hashiguchi Y, Sugihara K, Japanese Society for Cancer of the Colon, Rectum. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer. Int J Clin Oncol. 2021, 26, 8, 1353-419, doi: 10.1007/s10147-021-01881-4.（遺伝性大腸癌診療ガイドライン２０２０年版英語論文）(IF= 3.850)

 

92.   Morita S, Goda K, Yano T, Kaise M, Kato M, Inoue H, Niwa Y, Kodashima　S, Miyahara R, Ochiai A, Ikegami M, Ha00209-8matani S, Shimoda T, Ohkura Y, Aida J, Nakanishi Y, Takubo K, Yoshimura K, Ishikawa H, Muto M. Multicenter prospective in vivo study of Endocytoscope System (ECS) for superficial esophageal cancer. J Gastroenterol. 2021, 56, 9, 808-13, doi: 10.1007/s00535-021-01810-2. (IF= 6.772) 

 

93.   Ogawa-Ochiai K, Ishikawa H, Li H, Quang LV, Kimoto I, Takamura M, Hongawa T, Hane Y, Suzuki S, Okajima M, Mori K, Ito M, Takami A.Immunological and preventive effects of hochuekkito and kakkonto against coronavirus disease in healthcare workers: A retrospective observationalstudy.FrontPharmacol.2021,12,766402.doi:10.3389/fphar.2021.766402. (IF= 5.988) 

 

94. Nishida K, Morishima Y, Pascual-Marqui RD, Minami S, Yamane T,Michikura M, Ishikawa H, Kinoshita T. Mindfulness augmentation for anxiety     through concurrent use of transcranial direct current stimulation: a randomized double-blind study. Sci Rep. 2021, 11, 1,22734, doi: 10.1038/s41598-021-02177-3. (IF= 4.996)

 

95. Shimamoto Y, Ishiguro S, Takeuchi Y, Nakatsuka S, Yunokizaki H, Ezoe Y, Nakajima T, Matsuno K, Nakahira H, Tanaka K, Ishihara R, Takayama T, Yoshida T, Ishikawa H. Gastric Neoplasms in Patients with Familial Adenomatous Polyposis, Endoscopic and Clinicopathological Features. Gastrointest endosc. 2021, 94,6,1030-42. e2. doi: 10.1016/j.gie.2021.06.010. (IF= 10.396)

 

96. Ogawa-Ochiai, K, Osuga K, Nozaki T, Tazuke Y, Sakai S, Uehara S,Hoshi R, Ishikawa H, Yoshimura K, Okuyama H. Effect of Japanese Kampo medicine, eppikajutsuto, in patients with lymphatic malformation: A retrospective observational study.  Medicine (Baltimore). 2021, 100, 51, e28420, doi: 10.1097/MD.0000000000028420. (IF= 1.889)

 

97. Hasuo H, Ishikawa H, Matsuoka H. Relationship between the number of breaths that maximizes heart rate variability and height in patients with incurable cancers. Complement Ther Med. 2021, 5, 63, 102780. doi: 10.1016/j.ctim.2021.102780. (IF= 2.446)

 

98.   Morita M, Iizuka-Ohashi M, Watanabe M, Narita T, Kato C, KakibuchiD, Kitano F, Ouchi Y, Sakaguchi K, Taguchi T. Oxidative stress induces EGFR inhibition-related skin cell death. J Clin Biochem Nutr 68(3):235-242, 2021. (IF= 3.179)

 

99. 武藤倫弘, 中尾俊雅, 藤井元. 免疫学的アプローチによるがん予防の可能

 性. J・JSMUFF 14(4): 1-5, 2021.

 

100. 石川秀樹. がんの化学予防 2．アスピリンによる大腸腺腫、大腸癌の化予防. 癌と化学療法. 1425-8, 2021.

 

101. 石川秀樹. 家族性大腸腺腫症. 週刊日本医事新報. 34-5, 2021.

 

102. 秋山泰樹, 荒瀬光一, 永田淳, 井上譲, 鳥越貴行, 遠山篤史, 富崎一向,石井雅宏, 島尻正平, 田中久美子, 吉野潔, 藤本直浩, 高山哲治, 石川秀樹, 石田秀行, 平田敬治.デスモイド腫瘍による尿性腹水をきたした家族性大腸腺腫症の1 例. 遺伝性腫瘍. 36-40, 2021.

 

 2020年

103. Terasaki M, Kuramitsu Y, Kojoma M, Kim S-Y, Tanaka T, Maeda H, Miyashita K, Kawagoe C, Kohno S, Mutoh M. High fucoxanthin wakame (Undaria pinnatifida) prevents tumor microenvironment formation in an AOM/DSS mouse carcinogenic model. J Functional Foods. 2020 Jan 64, 103709. doi.org/10.1016/j.jff.2019.103709

 

104. Terasaki M, Ikuta M, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M. Dietary fucoxanthin induces anoikis in colorectal adenocarcinoma through suppressing integrin signaling in a murine colorectal cancer model. J. Clin. Med. 2020, 9(1), 90; doi.org/10.3390/jcm9010090

 

105. Kurokawa Y, Fujii G, Tomono S, Shingo M, Hamoya T, Takahashi M, Narita T, Komiya M, Kobayashi M, Higami Y, Mutoh M. The radical scavenger NZ-419 suppresses intestinal polyp development in Apc-mutant mice. J Clin Med. 2020 Jan 18;9(1). pii: E270. doi: 10.3390/jcm9010270.

 

106. Adachi S, Hamoya T, Fujii G, Narita T, Komiya M, Miyamoto S, Kurokawa Y, Takahashi M, Takayama T, Ishikawa H, Tashiro K, Mutoh M. Theracurmin inhibits intestinal polyp development in Apc-mutant mice by inhibiting inflammation-related factors. Cancer Sci. 2020 Apr;111(4):1367-1374. doi: 10.1111/cas.14329.

 

107. Kawanishi M, Shimohara C, Oda Y, Hisatomi Y, Tsunematsu Y, Sato M, Hirayama Y, Miyoshi N, Iwashita Y, Yoshikawa Y, Sugimura H, Mutoh M, Ishikawa H, Wakabayashi K, Yagi T, Watanabe K. Genotyping of a gene cluster for production of colibactin and in vitro genotoxicity analysis of Escherichia coli strains obtained from the Japan Collection of Microorganisms.  Genes Environ. 2020 Mar 11;42:12. doi: 10.1186/s41021-020-00149-z.

 

108. Yin T, Bayanjargal S, Fang B, Inaba C, Mutoh M, Kawahara T, Tanaka S, Watanabe J.  Lactobacillus plantarum Shinshu N-07 isolated from fermented Brassica rapa L. attenuates visceral fat accumulation induced by high-fat diet in mice. Beneficial Microbes. 2020 11 (7); 655-667. doi.org/10.3920/BM2020.0009

 

109. 武藤倫弘, 飯泉陽介, 藤井元. がん予防学の科学的・社会的側面。特集：環境因子と発がん,　実験医学39(11), 1862-1866, 2020.

 

110. 武藤倫弘, 成田匠, 藤井元. 大腸がん予防剤としてのアスピリンの歴史と現状の課題. 京都府立医科大学雑誌, 129(7), 469-477, 2020.

 

111. Ishikawa H, Mutoh M, Yoshimura K, Fujii G, Nakamura T, Takeshita T, Wakabayashi K, Sakai T. Very long-term treatment with a Lactobacillus probiotic preparation, Lactobacillus Casei strain Shirota, suppresses weight loss in the elderly. Nutrients. 2020 May 29;12(6):1599. doi: 10.3390/nu12061599.

 

112. 武藤倫弘, 曽和義広, 藤井元.日本におけるゲノムリスク告知の現状と課題.日中医学, 35(3), 21-25, 2020.

 

113. Terasaki M, Kimura R, Kubota A, Kojima H, Tanaka T, Maeda H, Miyashita K, Mutoh M. Continuity of tumor microenvironmental suppression in AOM/DSS mice by fucoxanthin may be able to track with salivary glycine. In Vivo. Nov-Dec 2020;34(6):3205-3215. doi: 10.21873/invivo.12156.

 

114. YoshikawaY, Tsunematsu Y, Matsuzaki N, Hirayama Y, Higashiguchi F, Sato M, Iwashita Y, Miyoshi N, Mutoh M, Ishikawa H, Sugimura H, Wakabayashi K, Watanabe K. Characterization of colibactin-producing Escherichia coli isolated from Japanese patients with colorectal cancer. Jpn J Infect Dis. 2020 Nov 24;73(6):437-442. doi: 10.7883/yoken.JJID.2020.066.

 

115. Umemura S, Sowa Y, Iizumi Y, Kitawaki J, Sakai T. Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression. Cancer Sci. 2020 Jun;111(6):2052-2061. doi: 10.1111/cas.14414.

 

116. Chihara Y, Iizumi Y, Horinaka M, Watanabe M, Goi W, Morita M, Nishimoto E, Sowa Y, Yamada T, Takayama K, Sakai T. Histone deacetylase inhibitor OBP 801 and amrubicin synergistically inhibit the growth of squamous cell lung carcinoma by inducing mitochondrial ASK1 dependent apoptosis. Int J Oncol. 2020 Mar;56(3):848-856. doi: 10.3892/ijo.2020.4969.

 

117. Miyamoto K, Watanabe M*†, Boku S, Sukeno M, Morita M, Kondo H, Sakaguchi K, Taguchi T, Sakai T. xCT Inhibition increases sensitivity to vorinostat in a ROS-dependent manner. Cancers (Basel). 2020 Mar 30;12(4):827. doi: 10.3390/cancers12040827. (*equal contribution, †corresponding author)

 

118. Boku S, Watanabe M†, Sukeno M, Yaoi T, Hirota K, Iizuka-Ohashi M, Itoh K, Sakai T. Deactivation of glutaminolysis sensitizes PIK3CA-mutated colorectal cancer cells to aspirin-induced growth inhibition. Cancers (Basel). 2020 Apr 30;12(5):1097. doi: 10.3390/cancers12051097. (†corresponding author)

 

119. Yokoyama A, Katada C, Yokoyama T, Takizawa K, Yano T, Oda I, Shimizu Y, Nakanishi H, Koike T, Hirao M, Okada H, Yoshii T, Katagiri A, Yamanouchi T, Matsuo Y, Kawakubo H, Kobayashi N, Ishikawa H, Muto M. The alcohol use disorders identification test and the risk of metachronous cancer after endoscopic resection of esophageal cancer. Carcinogenesis. 2020 Aug 12;41(8):1049-1056. doi:10.1093/carcin/bgaa022

 

120. Yokoyama A, Katada C, Yokoyama T, Takizawa K, Yano T, Oda I, Shimizu Y, Nakanishi H, Koike T, Hirao M, Okada H, Yoshii T, Katagiri A, Yamanouchi T, Matsuo Y, Kawakubo H, Kobayashi N, Ishikawa H, Muto M. Association between the findings of metachronous secondary primary malignancies and the number of Lugol-voiding lesions. Dis Esophagus. 2020 Sep 4;33(9):doz110. doi: 10.1093/dote/doz110.

 

121. Yoshida N, Doyama H, Yano T, Horimatsu T, Uedo N, Yamamoto Y, Kakushima N, Kanzaki H, Hori S, Yao K, Oda I, Katada C, Yokoi C, Ohata K, Yoshimura K, Ishikawa H, Muto M. Early gastric cancer detection in high-risk patients: a multicentre randomised controlled trial on the effect of second-generation narrow band imaging. Gut. 2021 Jan;70(1):67-75. doi: 10.1136/gutjnl-2019-319631.

 

122. 石川秀樹. 消化管ポリポーシス, 新臨床内科学, 2020, 573-575.

 

123. Ogawa-Ochiai K, Yoshimura K, Shirai A, Sakai S, Moriyama H, Nakamura K, Murayama T, Ishikawa H. Study protocol for daiobotanpito combined with antibiotic therapy for treatment of acute diverticulitis: a study protocol for a randomized controlled trial. Trials. 2020 Jun 16;21(1):531. doi: 10.1186/s13063-020-04370-7.

 

124. Oda I, Shimizu Y, Yoshio T, Katada C, Yokoyama T, Yano T, Suzuki H, Abiko S, Takemura K, Koike T, Takizawa K, Hirao M, Okada H, Yoshii T, Katagiri A, Yamanouchi T, Matsuo Y, Kawakubo H, Kobayashi N, Shimoda T, Ochiai A, Ishikawa H, Yokoyama A, Muto M. Long-term outcome of endoscopic mucosal resection for intramucosal esophageal squamous cell cancer: a secondary analysis of the Japan Esophageal Cohort study. Endoscopy. 2020 Nov;52(11):967-975. doi: 10.1055/a-1185-9329.

 

125. Hamada K, Kanzaki H, Inoue M, Ishiyama S, Yamauchi K, Miyahara K, Toyokawa T, Tsuzuki T, Miyaike J, Matsubara M, Takahashi S, Nishimura M, Takenaka R, Yunoki N, Hori S, Kobayashi S, Yamasaki Y, Kawahara Y, Ishikawa H, Okada H. Continued aspirin treatment may be a risk factor of delayed bleeding after gastric endoscopic submucosal dissection under heparin replacement: a retrospective multicenter study. Intern Med. 2020 Nov 1;59(21):2643-2651. doi: 10.2169/internalmedicine.4998-20.

 

126. Shinozaki T, Katada C, Shiga K, Asakage T, Yokoyama T, Yano T, Oda I, Shimizu Y, Takemura K, Ishikawa H, Yokoyama A, Muto M. Effectiveness of planned surveillance fordetecting second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma. Jpn J Clin Oncol. 2020 Sep 28;50(10):1162-1167. doi: 10.1093/jjco/hyaa087.

 

127. Yamada S, Fujii T, Yamamoto T, Takami H, Yoshioka I, Yamaki S, Sonohara F, Shibuya K, Motoi F, Hirano S, Murakami Y, Inoue H, Hayashi M, Murotani K, Kitayama J, Ishikawa H, Kodera Y, Sekimoto M, Satoi S, Phase I/II study of adding intraperitoneal paclitaxel in patients with pancreatic cancer and peritoneal metastasis. Br J Surg. 2020 Dec;107(13):1811-1817. doi: 10.1002/bjs.11792.

 

128. Kakushima N, Yoshida N, Doyama H, Yano T, Horimatsu T, Uedo N, Yamamoto Y, Kanzaki H, Hori S, Yao K, Oda I, Tanabe S, Yokoi C, Ohata K, Yoshimura K, Ishikawa H, Muto M. Near-focus magnification and second-generation narrow-band imaging for early gastric cancer in a randomized trial. J Gastroenterol. 2020 Dec;55(12):1127-1137. doi: 10.1007/s00535-020-01734-3.

 

129. 石田秀行，近谷賢一，母里淑子，百瀬修二，長田久人，山野智基，冨田尚裕，秋山泰樹，平田敬治，六車直樹，高山哲治，西田佳弘，石川秀樹. 家族性大腸腺腫症に合併するデスモイド腫瘍の診断・治療と重症度分類の提案. 遺伝性腫瘍. 2020, 20, 245-58.

 

130. 石川秀樹, 池浦司, 岡崎和一. 自己免疫性膵炎の最前線 コラム(2)：IgG4関連疾患患者レジストリ, 胆と膵. 2020, 41, 10, 1031-1035.

 

131. Hamada K, Kanzaki H, Inoue M, Ishiyama S, Yamauchi K, Miyahara K, Toyokawa T, Tsuzuki T, Miyaike J, Matsubara M, Takahashi S, Nishimura M, Takenaka R, Yunoki N, Hori S, Kobayashi S, Yamasaki Y, Kawahara Y, Ishikawa H, Okada H. Continued aspirin treatment may be a risk factor of delayed bleeding after gastric endoscopic submucosal dissection under heparin replacement: a retrospective multicenter study. Intern Med. 2020 Nov 1;59(21):2643-2651. doi: 10.2169/internalmedicine.4998-20.

 

著書業績

2023年

1. 武藤倫弘, 宮本真吾, 藤井元. I総論　大腸癌リスク因子　最新臨床大腸癌学2023 日本臨床81巻増刊号５　p12-16

 

2. 武藤倫弘, 藤井元. 5がん化学予防の最前線. 第４版アンチエイジング医学の基礎と臨床. 編集：日本抗加齢医学会　認定テキスト改訂版編集委員会p387-388 (メジカルビュー社) 6月出版

 

3. 石川秀樹. 第10章 難病の疫学「難病のレジストリ」. 疫学の辞典. 章編集者 中村好一. 監修 日本疫学会. 株式会社朝倉書店, 東京：pp218-219.

 

2021年

4. 武藤倫弘. ひと目でわかる実装科学：がん対策実践家のためのガイド」(翻訳の全体監修)

 

2020年

5. Mutoh M, Narita T, Ishikawa H. Chemoprevention for Lynch Syndrome-Associated Malignancies: Lynch Syndrome. In Tomita N, Editor. Springer Publishers, Basel, Switzerland: pp123-132, 2020.

 

6. 曽和義広, 酒井敏行.　「入門腫瘍内科学　改定第3版」　日本臨床腫瘍学会編集　南江堂