Affiliation

Department of Cardiovascular Medicine and Nephrology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine (Professor, 2015–)

Overseas Training / Roles

National Institutes of Health (NHLBI), USA — Cardiology Postdoctoral Research Fellow (2003); Director, Japanese Circulation Society; Vice-President, KPUM Hospital

Major Research Fields

Cardiovascular Medicine · Vascular Regenerative Medicine (CLTI) · Cardiac Cell Death & Mitochondria · Structural Heart Disease (TAVR) · Cardiovascular Epidemiology & Longevity

Professor Satoaki Matoba is Chair of the Department of Cardiovascular Medicine and Nephrology and Vice President of Kyoto Prefectural University of Medicine (KPUM). Following training at the U.S. National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI), he has established a broad cardiovascular research program spanning cardiac cell death and caveolae biology, vascular regenerative medicine, structural heart disease, and large-scale clinical research.
As a senior author and principal investigator, Professor Matoba has led cardiovascular research at KPUM to publication in leading international journals, supported by translational research funding from the Japan Agency for Medical Research and Development (AMED). His work has appeared in premier journals including The New England Journal of Medicine, Cell, Science Translational Medicine, and Nature Communications. Since 2022, the cumulative impact factor of his ten most influential publications has exceeded 190, reflecting the international impact and translational significance of his research.
Professor Matoba’s research is strongly supported by AMED programs. Over the past decade, he has ranked 7th among all principal investigators at KPUM in cumulative AMED funding, securing ¥84.0 million across two PI-led projects focused on vascular regenerative therapies for critical limb-threatening ischemia (CLTI). These projects include a bone marrow cell–based regenerative therapy and the development of a near-infrared tissue oxygenation (StO₂) monitoring device. He also ranks 10th in cumulative individual AMED funding allocation as a co-investigator in national cardiovascular disease research consortia. Professor Matoba serves as a Director of the Japanese Circulation Society and several other academic societies and contributes to the Kyotango Longevity Cohort, which investigates the relationships among lifestyle, gut microbiota, and healthy ageing.

Kyotango area, northern area of Kyoto, is famous for its healthy longevity. Number of centenarian is 2.8 times of the average of Japanese. Mr. Jirouemon Kimura, who ceased at 116 years old, is a Guines record holder of male longevity, was born in here and lived his whole life in Kyotango area. Researchers of our university have started the longevity cohort study since 2017. We are collecting about 2000 data from one participant and 1200　people are checking their health record every 3 years. We published many papers and we held the first longevity summit last year. The joint declaration outlined four pillars for healthy aging are bonds with communication, dietary fiber, physical activity, and “Ikigai”, a sense of purpose. Please let us know about collaboration of the research for healthy longevity.