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Obstetrics and Gynecology

Subject Obstetrics and Gynecology
Staff
Professor Jo Kitawaki
 
 
professor:Kazuhiro Iwasaku
Associate Professor: Izumi Kusuki, Khan Khaleque,
Lecturer:Taisuke Mori, Haruno Kuroboshi .
Assistant Professor: Miyoko Waratani, Akemi Koshiba, Hiroshi Matsushima,
                              Shiori Umemura, Fumitake Itoh, Takuro Yamamoto,
                              Tetsuro Tsugi, Osamu Takaoka, Kohei Aoyama,
                              Nanami Tsukasaki, Kouki Shimura.
Research Contents
Our department consists of teams of physicians/researchers with highly specialized expertise in every area of Ob-Gyn.
 
1) Maternal and fetal medicine: As a subcenter of perinatal medical care in Kyoto prefecture, we accept women with high-risk pregnancy or maternal transport anytime.
2) Perinatal remote diagnosis system: We are a member of the perinatal healthcare network consisting of 19 perinatal medical centers across the prefecture, working on remote diagnosis by fetal sonography.
3) Basic and clinical research in endometriosis: To clarify the pathogenic mechanism and establish new treatment strategy, we focus on hormonal environment, immune system, and inflammatory response of endometriosis patients.
4) We are engaged in developing a novel serum marker for early diagnosis of endometriosis.
5) We provide multidisciplinary therapy for severe endometriosis aiming to improve fertility.
6) Gynecologic oncology: Our basic research on cancer development mechanism aims to discover the biomarker and growth-regulatory factor, for early diagnosis and more effective treatment.
7) Oncofertility: We provide the fertility-sparing treatment/surgery for cancer patients in adolescence and young age (AYA).        
8) We have accumulated experience of laparoscopic or robot-assisted surgery for gynecologic tumors.
9) We are analyzing anti-aging effects of endocrine therapies to develop a new treatment concept.
Achievements
Mori T, et al. Dienogest reduces HSD17β1 expression and activity in endometriosis. J Endocrinol [Epub ahead of print]
 
Mori T, et al., G protein-coupled estrogen receptor 1 agonist G-1 induces cell cycle arrest in the mitotic phase, leading to apoptosis in endometriosis. Fertil Steril [Epub ahead of print]
 
Suganuma I, et al. Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha enhances local estrogen biosynthesis by stimulating aromatase activity in endometriosis. J Clin Endocrinol Metab 99: E1191-E1198, 2014
 
Ito F, et al. Medroxyprogesterone acetate enhances monocyte-endothelial interaction under flow conditions by stimulating the expression of cell adhesion molecules. J Clin Endocrinol Metab 99: 2188-2197, 2014
 
Kusuki I, et al. Usefulness of moistening Seprafilm before use in laparoscopic surgery Surg Laparosc Endosc Percutan Tech 24:e13-5, 2014.
 
Minami T, et al. Antiproliferative and apoptotic effects of norethisterone on endometriotic stromal cells in vitro. Eur J Obstet Gynecol Reprod Biol 166:76-80, 2013.
 
Yamamoto T, et al. Estrogen-related receptor-γ regulates estrogen receptor-α responsiveness in uterine endometrial cancer. Int J Gynecol Cancer 22:1509-1516, 2012.
 
Yamanaka K, et al. Dienogest inhibits aromatase and cyclooxygenase-2 expression and prostaglandin E2 production in human endometriotic stromal cells in spheroid culture. Fertil Steril 97:477-482, 2012.
 
Kitawaki J, et al. Maintenance therapy with dienogest following gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain. Eur J Obstet Gynecol Reprod Biol 157:212-216, 2011.
 
Mori T, et al. Estrogen-related receptor α expression and function are associated with vascular endothelial growth factor in human cervical cancer. Int J Gynecol Cancer 21:609-615, 2011.
Contact TEL: 81-75-251-5560 
FAX: 81-75-212-1265
e-mail:aoi#koto.kpu-m.ac.jp(please replace # with @)
HP

602-8566 Kyoto-shi, Kamigyo-ku Kajii-cho,
Kawaramachi-Hirokoji, JAPAN

Contact
TEL:075-251-5111
FAX:075-251-7093