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Department of Pediatric Surgery

Subject Department of Pediatric Surgery
Staff
Professor Tatsuro Tajiri
 
 
Associate Professor : Taizo Furukawa
Lecturer : Shigeyoshi Aoi
Assistant Professor : Shigehisa Fumino, Mayumi Higashi, Kohei Sakai
Research Cotents
  1. Development of novel treatment for advanced neuroblastoma
  2. Development of novel fetal therapy for severe congental diaphragmatic hernia
Achievements
1) Fumino S, Kimura K, Iehara T, Nishimura M, Nakamura S, Souzaki R, Nishie A, Taguchi T, Hosoi H, Tajiri T: Validity of image-defined risk factors in localized neuroblastoma: A report from two centers in Western Japan. J Pediatr Surg, 50: 2102-2106, 2015
2) Higashi M, Kolla V, Iyer R, Naraparaju K, Zhuang T, Kolla S, Brodeur GM: Retinoic acidinduced CHD5 upregulation and neuronal differentiation of neuroblastoma. Mol Cancer, 14: 150, 2015.
3) Tanaka T, Higashi M, Kimura K, Wakao J, Fumino S, Iehara T, Hosoi H, Sakai T, Tajiri T : MEK inhibitors as a novel therapy for neuroblastoma: Their in vitro effects and predicting their efficacy. J Pediatr Surg, 51: 2074-2079, 2016.
4) Kimura K, Kishida T, Wakao J, Tanaka T, Higashi M, Fumino S, Aoi S, Furukawa T, Mazda O, Tajiri T: Tumor-homing effect of human mesenchymal stem cells in a TH-MYCN mouse model of neuroblastoma. J Pediatr Surg, 51: 2068-2073, 2016.
5) Takeuchi Y, Tanaka T, Higashi M, Fumino S, Iehara T, Hosoi H, Sakai T, Tajiri T: In vivo effects of short- and long-term MAPK pathway inhibition against neuroblastoma. J Pediatr Surg, 53: 2454-2459, 2018.
6) Higashi M, Sakai K, Fumino S, Aoi S, Furukawa T, Tajiri T: The roles played by the MYCN, Trk, and ALK genes in neuroblastoma and neural development. Surg Today, 2019, in press.
7) Maniwa J, Fumino S, Kimura K, Tanaka T, Higashi M, Kishida T, Mazda O, Tajiri T: Novel mesenchymal stem cell delivery system as targeted therapy for neuroblastoma using the TH-MYCN mouse model. J Pediatr Surg, 2019, in press.
8) Sakai K, Kimura O, Furukawa T, Fumino S, Higuchi K, Wakao J, Kimura K, Aoi S, Masumoto K, Tajiri T: Prenatal administration of neuropeptide bombesin promotes lung development in a rat model of nitrofen-induced congenital diaphragmatic hernia. J Pediatr Surg 49: 1749-1752, 2014.
9) Furukawa T, Kimura O, Sakai K, Higashi M, Fumino S, Aoi S, Tajiri T: Surgical intervention strategies for pediatric congenital cystic lesions of the lungs: A 20-year single-institution experience. J Pediatr Surg 50: 2025-2027, 2015.
10) Wakao J, Kishida T, Fumino S, Kimura K, Yamamoto K, Kotani S, Mizushima K, NaitoY, Yoshikawa T, Tajiri T, Mazda O: Efficient direct conversion of human fibroblasts intomyogenic lineage induced by co-transduction with MYCL and MYOD1. Biochem BiophysRes Commun, 488: 368-373, 2017.
Contact TEL:81-75-251-5809
FAX:81-75-251-5828
e-mail: pedsurg@koto.kpu-m.ac.jp
HP http://pedsurg.kpu-m.ac.jp/index.php
 

 

602-8566 Kyoto-shi, Kamigyo-ku Kajii-cho,
Kawaramachi-Hirokoji, JAPAN

Contact
TEL:075-251-5111
FAX:075-251-7093