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Department of Ophthalmology

Subject Department of Ophthalmology
Staff
Professor
Chie Sotozono
Associate Professor:  Norihiko Yokoi
Lecturer:  Kazuhiko Mori, Tsutomu Inatomi
Assistant Professor:  Osamu Hieda, Morio Ueno, Akihide Watanabe, 
Kentaro Kojima,Sayaka Kamata,Yoshinori Nakai, Kenji Nagata
Research Contents  
Achievements
  1. Yokoi N,Georgiev GA.Tear film-oriented diagnosis and tear film-oriented therapy for dry eye based on tear film dynamics.Invest Ophthalmol Vis Sci.59(14): DES13-DES22,2018.
  2. Sotozono C,Ueta M,Yokoi N.Severe Dry Eye With Combined Mechanisms is Involved in the Ocular Sequelae of SJS/TEN at the Chronic Stage.Invest Ophthalmol Vis Sci.59(14): 80-86,2018.
  3. Ueta M.Results of detailed investigations into Stevens-Johnson Syndrome with severe ocular complications.Invest Ophthalmol Vis Sci.59(14): DES183-DES191,2018.
  4. Kinoshita S,Koizumi N,Ueno M,Okumura N,Imai K,Tanaka H,Yamamoto Y,Nakamura T,Inatomi T,Bush J,Toda M,Hagiya M,Yokota I,Teramukai S,Sotozono C,Hamuro J.Injection of Cultured Cells with a ROCK Inhibitor for Bullous Keratopathy.N Engl J Med. 378(11): 995-1003,2018.(IF=79.258)
  5. Uchino M,Kawashima M,Uchino Y,Suzuki N,Mitamura H,Mizuno M,Hori Y,Yokoi N,Tsubota K.The evaluation of dry eye mobile apps for screening of dry eye disease and educational tear event in Japan.Ocul Surf.16(4): 430-435,2018.(IF=9.108)
  6. Vu CHV,Kawashima M,Yamada M,Suwaki K,Uchino M,Shigeyasu C,Hiratsuka Y,Yokoi N,Tsubota K,Dry Eye Cross-Sectional study in Japan study group.Influence of meibomian gland dysfunction and friction-related disease on the severity of dry eye.Ophthalmology.125(8): 1181-1188,2018.(IF=7.732)
  7. Lee HK,Yoon KC,Seo KY,Ueta M,Kim MK.Chronic ocular complications of Stevens-Johnson syndrome associated with causative medications in Korea.J Allergy Clin Immunol Pract.6(2): 700-702.e2,2018.(IF=7.550)
  8. Ueta M,Hamuro J,Nishigaki H,Nakamura N,Shinomiya K,Mizushima K,Hitomi Y,Tamagawa-Mineoka R,Yokoi N,Naito Y,Tokunaga K,Katoh N,Sotozono C,Kinoshita S.Mucocutaneous Inflammation in the Ikaros Family Zinc Finger 1 (IKZF1) - keratin 5 specifc transgenic mice.Allergy.73(2): 395-404,2018.(IF=6.771)
  9. Su SC,Chen CB,Chang WC,Wang CW,Fan WL,Lu LY,Nakamura R,Saito Y,Ueta M,Kinoshita S,Sukasem C,Yampayon K,Kijsanayotin P,Nakkam N,Saksit N,Tassaneeyakul W.HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians.Clin Pharmacol Ther.105(2):476-485,2018.(IF=6.336)
  10. Kinoshita S.The Ongoing Puzzle of the Biological Behavior of Cornea Guttae.JAMA Ophthalmol.136(8): 893-894,2018.(IF=6.167)
  11. Khor WB,Prajna VN,Garg P,Mehta JS,Xie L,Liu Z,Padilla MDB,Joo CK,Inoue Y,Goseyarakwong P,Hu FR,Nishida K,Kinoshita S,Puangsricharern V,Tan AL,Beuerman R.The Asia Cornea Society Infectious Keratitis Study: A Prospective Multicenter Study Of Infectious Keratitis In Asia.Am J Ophthalmol.195(11): 161-170,2018.(IF=4.483)
  12. Nencheva Y,Ramasubramanian A,Eftimov P,Yokoi N,Borchman D,Georgiev GA.Effects of lipid saturation on the surface properties of human meibum films.Int J Mol Sci.19(8): E2209,2018.(IF=4.183)
  13. Cehofski LJ,Kruse A,Kirkeby S,Alsing AN,Ellegaard Nielsen J,Kojima K,Honoré B,Vorum H.IL-18 and S100A12 Are Upregulated in Experimental Central Retinal Vein Occlusion.Int J Mol Sci.19(11): 3328,2018.(IF=4.183)
  14. Shinomiya K,Ueta M,Kinoshita S.A new dry eye mouse model produced by exorbital and intraorbital lacrimal gland excision.Sci Rep.8(1): 1483,2018.(IF=4.011)
  15. Terao N,Koizumi H,Kojima K,Yamagishi T,Yamamoto Y,Yoshii K,Kitazawa K,Hiraga A,Toda M,Kinoshita S,Sotozono C,Hamuro J.Distinct Aqueous Humour Cytokine Profiles of Patients with Pachychoroid Neovasculopathy and Neovascular Age-related Macular Degeneration. Sci Rep.8(1): 10520,2018.(IF=4.011)
  16. Ouchi M,Shiba T.Diffractive multifocal intraocular lens implantation in eyes with a small-diameter pupil. Sci Rep.8(1):11686,2018.(IF=4.011)
  17. Morgan SR,Hieda O,Nakai Y,Boote C,Hayes S,Kinoshita S,Meek KM,Quantock AJ.Microwave treatment of the cornea leads to localised disruption of the extracellular matrix.Sci Rep.8(1): 13742,2018.(IF=4.011)
  18. Kitazawa K,Itoi M,Yokota I,Wakimasu K,Cho Y,Nakamura Y,Hieda O,Kinoshita S,Sotozono C.Involvement of anterior and posterior corneal surface area imbalance in the pathological change of keratoconus.Sci Rep.8(1): 14993,2018.(IF=4.011)
  19. Tamagawa-Mineoka R,Yasuoka N,Ueta M,Katoh N.Influence of topical steroids on intraocular pressure in patients with atopic dermatitis.Allergol Int.67(3): 388-391,2018.(IF=3.965)
  20. Terao N,Koizumi H,Kojima K,Yamagishi T,Nagata K,Kitazawa K,Yamamoto Y,Yoshii K,Hiraga A,Toda M,Kinoshita S,Sotozono C,Hamuro J.Association of Upregulated Angiogenic Cytokines With Choroidal Abnormalities in Chronic Central Serous Chorioretinopathy.Invest Ophthalmol Vis Sci.59(15): 5924-5931,2018.(IF=3.812)
  21. Yamanaka Y,Watanabe A,Sotozono C,Kinoshita S.Impact of surgical timing of postoperative ocular motility in orbital blowout fractures. Br J Ophthalmol.102(3): 398-403,2018.(IF=3.384)
  22. Jongkhajornpong P,Lekhanont K,Pisuchpen P,Chantaren P,Puangsricharern V,Prabhasawat P,Suphapeetiporn K,Kinoshita S,Ueta M.Association between HLA-B*44:03-HLA-C*07:01 haplotype and cold medicine-related Stevens-Johnson syndrome with severe ocular complications in Thailand.Br J Ophthalmol.102(9): 1303-1307,2018.(IF=3.384)
  23. Kitazawa K,Jongkhajornpong P,Koizumi N,Koizumi N,Kayukawa K,Wakimasu K,Sotozono C,Kinoshita S.Topical ganciclovir treatment post-Descemet's stripping automated endothelial keratoplasty for patients with bullous keratopathy induced by cytomegalovirus. Br J Ophthalmol.102(9): 1293-1297,2018.(IF=3.384)
  24. Deguchi H,Kayukawa K,Kayukawa K,Kondoh E,Fukumoto A,Yamasaki T,Kinoshita S,Sotozono C.The trend of resistance to antibiotics for ocular infection of Staphylococcus aureus, coagulase-negative staphylococci, and Corynebacterium compared with 10-years previous: A retrospective observational study.PLoS One.13(9): e0203705,2018.(IF=2.776)
  25. Okumura N,Matsumoto D,Fukui Y,Teramoto M,Imai H,Kurosawa T,Shimada T,Kruse F,Schlötzer-Schrehardt U,Kinoshita S,Koizumi N.Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model.PLoS One.13(1): e0191306,2018.(IF=2.776)
  26. Sunagawa Y, Funamoto M,Sono S,Shimizu K,Shimizu S,Genpei M,Miyazaki Y,Katanasaka Y,Morimoto E,Ueno M,Komiyama M,Kakeya H,Wada H,Hasegawa K,Morimoto T.Curcumin and its demethoxy derivatives possess p300 HAT inhibitory activity and suppress hypertrophic responses in cardiomyocytes.J Pharmacol Sci.136(4): 212-217,2018.(IF=2.439)
  27. Okumura N,Inoue R,Nakano S,Imai H,Matsumoto D,Kayukawa K,Wakimasu K,Kitazawa K,Koizumi N.Immune Cells on the Donor Corneal Endothelium after Corneal Transplantation.Cornea.37(9): 1081-1086,2018.(IF=2.313)
  28. Dohlman CH,Cade F,Regatieri CV,Zhou C,Lei F,Crnej A,Harissi-Dagher M,Robert MC,Papaliodis GN,Chen D,Aquavella JV,Akpek EK,Aldave AJ,Sippel KC,DʼAmico DJ,Dohlman JG.Chemical Burns of the Eye: The Role of Retinal Injury and New Therapeutic Possibilities.Cornea.37(2): 248-251,2018.(IF=2.313)
  29. Kitazawa K,Wakimasu K,Kayukawa K,Sugimoto M,Nakai J,Weiss JJ,Ueno M,Sotozono C.Long-Term Outcome After Penetrating Keratoplasty in a Pedigree with the G177E Mutation in the UBIAD1 Gene for Schnyder Corneal Dystrophy. Cornea.37(5): 554-559,2018.(IF=2.313)
  30. Noguchi A,Okumura N,Sotozono C,Kinoshita S.Effect of Posterior Corneal Vesicles on Corneal Endothelial Cell Density and Anisometropic Amblyopia.Cornea.37(7): 813-817,2018.(IF=2.313)
  31. Kitazawa K,Wakimasu K,Kayukawa K,Yokota I,Inatomi T,Hieda O,Sotozono C.Moderately Long-Term Safety and Efficacy of Repeat Penetrating Keratoplasty.Cornea.37(10): 1255-1259,2018.(IF=2.313)
  32. Miyazaki D,Shimizu D,Shimizu Y,Inoue Y,Inoue T,Higaki S,Ueta M,Sugita S.Real-time PCR for ocular cytomegalovirus infection study group. Diagnostic efficacy of real-time PCR for ocular cytomegalovirus infections.Graefes Arch Clin Exp Ophthalmol.256(12): 2413-2420,2018.(IF=2.250)
  33. Okumura N,Matsumoto D,Okazaki Y,Koizumi N,Sotozono C,Kinoshita S,Mori K.Wide-field contact specular microscopy analysis of corneal endothelium post trabeculectomy.Graefes Arch Clin Exp Ophthalmol.256(4): 751-757,2018.(IF=2.250)
  34. Stone JS,Fukuoka H,Weinreb RN,Afshari NA.Relationship Between Race, Insurance Coverage, and Visual Acuity at the Time of Cataract Surgery.Eye & Contact Lens Science & Clinical Practice.44(6):393-398,2018.(IF=1.813)
  35. Kitazawa K,Kayukawa K,Wakimasu K,Inatomi T,Hieda O,Mori K,Sotozono C.Topical non-steroidal anti-inflammatory drugs for the treatment of cystoid macular edema post Descemet's stripping automated endothelial keratoplasty.Jpn J Ophthalmol.62(6): 615-620,2018.(IF=1.653)
  36. Kanda H,Oshika T,Hiraoka T,Hasebe S,Ohno-Matsui K,Ishiko S,Hieda O,Torii H,Varnas SR,Fujikado T.Effect of spectacle lenses designed to reduce relative peripheral hyperopia on myopia progression in Japanese children: a 2-year multicenter randomized controlled trial.Jpn J Ophthalmol.62(5): 537-543,2018.(IF=1.653)
  37. Okumura N,Kusakabe A,Koizumi N,Wakimasu K,Kayukawa K,Kondo M,Mori K,Sotozono C,Kinoshita S.Endothelial cell loss and graft survival after penetrating keratoplasty for laser iridotomy-induced bullous keratopathy.Jpn J Ophthalmol.62(4): 438–442,2018.(IF=1.653)
  38. Yokoi N,Komuro A,Sotozono C,Kinoshita S.A new surgical approach for punctal occlusion using fibrous tissue from under the lacrimal caruncle.Clin Ophthalmol.12: 463-472,2018.(IF=1.28)
  39. Ueda K,Watanabe A,Yokoi N,Sugimoto M,Fukuoka H,Shinomiya K,Kinoshita S,Rajak S,Selva D.Biopsy of recurrent nasolacrimal duct obstruction using sheath-guided dacryoendoscopy.Orbit.38(1):37-42,2018.(IF=0.52)
  40. Mieno H,Yoneda K,Yamazaki M,Sakai R,Sotozono C,Fukui M.The Efficacy of Sodium-Glucose Cotransporter 2 (SGLT2) inhibitors for the treatment of chronic diabetic macular oedema in vitrectomised eyes:a retrospective study.BMJ Open Ophthalmology.3(1): e000130,2018.(IF=not yet decided)
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