Department of Chemistry

Subject Department of Chemistry
Staff
Professor
Takayoshi Suzuki
 
 
Assistant Professor Yukihiro Itoh
Research Contents
 Aiming to develop therapeutic agents, medicinal chemistry and chemical biology are conducted in our group. The focused fields of computational molecular design, synthetic reactions, and biological action mechanisms of bio-functional molecules are studied on the basis of organic chemistry.
Achievements
  1.  Ogasawara, D.; Itoh, Y.; et al. Lysine-Specific Demethylase 1-Selective Inactivators Based on Protein-Targeted Drug Delivery Mechanism. Angew. Chem. Int. Ed. 2013, 52, 8620–8624.
  2. Suzuki, T.; Miyata, N. Lysine Demethylase inhibitors. J. Med. Chem. 2011, 54, 8236–8250.
  3. Suzuki, T.; Ota, Y.; et al. An Unexpected Example of Protein-Templated Click Chemistry. Angew. Chem. Int. Ed. 2010, 49, 6817–6820.
  4. Ueda, R.; Suzuki, T.; et al. Identification of cell-active lysine specific demethylase 1-selective inhibitors. J. Am. Chem. Soc. 2009, 131, 17536–17537.
  5. Asaba, T.; Suzuki, T.; et al. Inhibition of Human Sirtuins by In Situ Generation of an Acetylated Lysine-ADP-ribose Conjugate. J. Am. Chem. Soc. 2009, 131, 6989–6996.
Contents
FAX:075-703-4937
TEL:075-703-4937
e-mail:suzukit@koto.kpu-m.ac.jp
HP  http://www.f.kpu-m.ac.jp/y/chemistry/English/index.html

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