小児外科学/外科学教室(小児外科学部門)

 小児外科HP http://www.f.kpu-m.ac.jp/k/pedsurg/

大学院科目名 小児外科学
医学部教室名 外科学教室(小児外科学部門)
スタッフ
教授  田尻 達郎
 
 
講師      古川 泰三
講師                  青井 重善
助教(学内講師)文野 誠久
助教      東 真弓
助教      坂井 宏平
研究内容
研究内容
主な基礎研究
(1) 間葉系幹細胞を用いた神経芽腫のhoming効果および分化誘導療法
(2) 新規分子標的薬を用いた神経芽腫治療の前臨床試験
(3) 先天性横隔膜ヘルニアにおける肺低形成の病態解析および胎児治療の開発
(4) 横隔膜全欠損に対する幹細胞を用いた横隔膜再生医療の開発
 
主な臨床研究
(1) リンパ管腫に対するmTOR阻害剤の臨床効果
(2) 新生児先天性横隔膜ヘルニアの治療標準化に関する研究
(3) 先天性横隔膜ヘルニア剖検症例の解析による胎児治療の開発
(4) 短腸症候群の包括的治療戦略の構築
(5) 新たな低侵襲手術治療の開発
研究業績
1) Furukawa T, Kimura O, Go S, Iwai N: Small bowel allografts maintained by administration of bombesin while under immunosupression. J Pediatr Surg 38: 83-87, 2003.
2) Kimura O, Ono S, Furukawa T, Higuchi K, Deguchi E, Iwai N: Management strategies for infants with total intestinal aganglionosis. J Pediatr Surg 44: 1564-1567, 2009.
3) Kimura O, Iwai N, Sasaki Y, Tsuda T, Deguchi E, Ono S, Furukawa T: Laparoscopic versus open abdominoperineal rectoplasty for infants with high type of anorectal malformation. J Pediatr Surg 45: 2390-2393, 2010.
4) Tajiri T, Kimura O, Fumino S, Furukawa T, Iehara T, Souzaki R, Kinoshita Y, Koga Y, Suminoe A, Hara T, Kohashi K, Oda Y, Hishiki T, Hosoi H, Hiyama E, Taguchi T: Surgical strategies for unresectable hepatoblastomas. J Pediatr Surg 47: 2194-2198, 2012.
5) Kimura O, Furukawa T, Higuchi K, Takeuchi Y, Fumino S, Aoi S, Tajiri T: Impact of our new protocol on the outcome of the neonates with congenital diaphragmatic hernia. Pediatr Surg Int 29: 335-339, 2013.
6) Fumino S, Higuchi K, Aoi S, Furukawa T, Kimura O, Tajiri T: Clinical analysis of liver fibrosis in choledochal cyst. Pediatr Surg Int 29:1097-1102, 2013.
7) Sakai K, Kimura K, Kimura O, Aoi S, Furukawa T, Masumoto K, Fumino S, Tajiri T. Prenatal administration of neuropeptide bombesin promotes lung development in a rat model of nitrofen-induced congenital diaphragmatic hernia. 49: 1749-1752, 2014.
8) Fumino S, Kimura K, Iehara T, Nishimura M, Nakamura S, Souzaki R, Nishie A, Taguchi T, Hosoi H,Tajiri T: Validity of image-defined risk factors in localized neuroblastoma: A report from two centers in Western Japan. J Pediatr Surg 50: 2102-2106, 2015.
9) Fumino S, Maniwa J, Takeuchi Y, Sakai K, Higashi M, Aoi S, Furukawa T, Kimura O, Tajiri T: Surgical intervention and perioperative risk factors of retroperitoneal teratomas in children: a single institution experience. Pediatr Surg Int 32: 909-914, 2016.
10) Tanaka T, Higashi M, Kimura K, Wakao J, Fumino S, Iehara T, Hosoi H, Sakai T, Tajiri T : MEK inhibitors as a novel therapy for neuroblastoma: Their in vitro effects and predicting their efficacy. J Pediatr Surg 51: 2074-2079, 2016.
11) Kimura K, Kishida T, Wakao J, Tanaka T, Higashi M, Fumino S, Aoi S, Furukawa T, Mazda O, Tajiri T: Tumor-homing effect of human mesenchymal stem cells in a TH-MYCN mouse model of neuroblastoma. J Pediatr Surg 51: 2068-2073, 2016.
問い合わせ先

TEL:075-251-5809
FAX:075-251-5828
e-mail:pedsurg@koto.kpu-m.ac.jp

教室独自のHP http://www.f.kpu-m.ac.jp/k/pedsurg/

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