小児外科学/外科学教室(小児外科学部門)

 小児外科HP http://www.f.kpu-m.ac.jp/k/pedsurg/

大学院科目名 小児外科学
医学部教室名 外科学教室(小児外科学部門)
スタッフ
教授  田尻 達郎
 
 
講師      古川 泰三
講師                  青井 重善
助教(学内講師)文野 誠久
助教      東 真弓
助教      坂井 宏平
研究内容
主な基礎研究
(1)難治性小児固形悪性腫瘍に対する新規治療法の開発
(2)神経芽腫4s期のiPS細胞疾患モデルによる同時多発・自然退縮メカニズムの解析
(3)先天性横隔膜ヘルニアにおける肺低形成の病態解析および胎児治療の開発
(4)先生性横隔膜ヘルニアにおけるiPS細胞を用いた自己筋膜シートの作成
 
主な臨床研究
(1)神経芽腫におけるIDRFに基づいた外科的治療戦略
(2)膵胆管合流異常症の術後遠隔成績の検討
(3)短腸症候群の包括的治療戦略の構築
(4)新たな低侵襲手術治療の開発 
研究業績
1) Tajiri T, Tanaka S, Shono K, Kinoshita Y, Fujii Y, Suita S, Ihara K, Hara T: Quick quantitative analysis of gene dosages associated with prognosis in neuroblastoma. Cancer Lett 166: 89-94, 2001.
2) Tajiri T, Shono K, Tanaka S, Suita S: Evaluation of genetic heterogeneity in neuroblastoma. Surgery 131: 283-287, 2002.
3) Tajiri T, Higashi M, Souzaki R, Tatsuta K, Kinoshita Y, Taguchi T: Classification of neuroblastomas based on an analysis of the expression of genes related to the prognosis. J Pediatr Surg 42: 2046-2049, 2007.
4) Higashi M, Tajiri T, Kinoshita Y, Tatsuta K, Souzaki R, Maehara Y, Suita S, Taguchi T: High expressions of neuronatin isoforms in favorable neuroblastoma. J Pediatr Hematol Oncol 29: 551-556, 2007.
5) Furukawa T, Kimura O, Go S, Iwai N: Small bowel allografts maintained by administration of bombesin while under immunosupression. J Pediatr Surg 38: 83-87, 2003.
6) Kimura O, Ono S, Furukawa T, Higuchi K, Deguchi E, Iwai N: Management strategies for infants with total intestinal aganglionosis. J Pediatr Surg 44: 1564-1567, 2009.
7) Kimura O, Iwai N, Sasaki Y, Tsuda T, Deguchi E, Ono S, Furukawa T: Laparoscopic versus open abdominoperineal rectoplasty for infants with high type of anorectal malformation. J Pediatr Surg 45: 2390-2393, 2010.
8) Tajiri T, Kimura O, Fumino S, Furukawa T, Iehara T, Souzaki R, Kinoshita Y, Koga Y, Suminoe A, Hara T, Kohashi K, Oda Y, Hishiki T, Hosoi H, Hiyama E, Taguchi T: Surgical strategies for unresectable hepatoblastomas. J Pediatr Surg 47: 2194-2198, 2012.
9) Kimura O, Furukawa T, Higuchi K, Takeuchi Y, Fumino S, Aoi S, Tajiri T: Impact of our new protocol on the outcome of the neonates with congenital diaphragmatic hernia. Pediatr Surg Int 29: 335-339, 2013.
10) Fumino S, Higuchi K, Aoi S, Furukawa T, Kimura O, Tajiri T: Clinical analysis of liver fibrosis in choledochal cyst. Pediatr Surg Int 29:1097-1102, 2013.
11) Sakai K, Kimura K, Kimura O, Aoi S, Furukawa T, Masumoto K, Fumino S, Tajiri T. Prenatal administration of neuropeptide bombesin promotes lung development in a rat model of nitrofen-induced congenital diaphragmatic hernia. 49: 1749-1752, 2014.
 12) Furukawa T, Aoi S, Sakai K, Higashi M, Fumino S, Tajiri T: Successful laparoscopic extirpation of a large omental lipoblastoma in a child. Asian J Endosc Surg 8: 473-476, 2015.
13) Fumino S, Kimura K, Iehara T, Nishimura M, Nakamura S, Souzaki R, Nishie A, Taguchi T, Hosoi H,Tajiri T: Validity of image-defined risk factors in localized neuroblastoma: A report from two centers in Western Japan. J Pediatr Surg 50: 2102-2106, 2015.
14) Furukawa T, Kimura O, Sakai K, Higashi M, Fumino S, Aoi S, Tajiri T: Surgical intervention strategies for pediatric congenital cystic lesions of the lungs: A 20-year single-institution experience. J Pediatr Surg 50: 2025-2027, 2015.
15) Fumino S, Maniwa J, Takeuchi Y, Sakai K, Higashi M, Aoi S, Furukawa T, Kimura O, Tajiri T: Surgical intervention and perioperative risk factors of retroperitoneal teratomas in children: a single institution experience. Pediatr Surg Int 32: 909-914, 2016.
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